Angiopoietin
The angiopoietins are protein growth factors that promote angiogenesis, the formation of blood vessels from pre-existing blood vessels.
The angiopoietins are the secreted ligands of the Tie family of protein receptor tyrosine kinases.
Angiopoietin 2 is elevated in patients with angiosarcoma.
Vaccination against TIE-2 + cells appears to reduce atheroma formation in experimental animals.ANGPTL1, ANGPTL2, ANGPTL5, Angiopoietin 1, Angiopoietin 2, Angiopoietin 3, Angiopoietin 4, TIE1, TIE2.