Oncology assays
We offer a set of in vitro efficacy tests using cellular tests for oncology studies:
- Cell Proliferation: A broad range of proliferation assays (MTT, Cell Titer Glo, BrdU incorporation) that can be used with a wide variety of cell types
- Apoptosis tests: Apoptosis tests are typically done by FACS but can also use a plate reader.
- Antibody binding on target cells: robust assays that allow sensitive and repeatable detection of binding events
- In Vitro Angiogenesis: In vitro angiogenesis factors are measured using tube formation by primary endothelial cells (typically primary HUVEC cells)
- Toxicity assays (eg ADCC, ADCP, CDC tests): Antibody Dependent Cell Cytotoxicity (ADCC) and Complement Dependent Cytotoxicity (CDC) Tests
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Antibody Dependent Cell Cytotoxicity (ADCC) and Complement Dependent Cytotoxicity (CDC) tests
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In vitro angiogenes is measured using tube formation by primary endothelial cells
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Assays that enable the sensitive and reproducible detection of binding events
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Apoptosis assays by FACS or by measurement with a plate reader
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Cell proliferation
Tumor cells are characterized by their rampant proliferation potential. We offer a broad range of proliferation assays (e.g. MTT, Cell Titer Glo, BrdU incorporation, etc.) that can be used on a variety of cell types. These assays are applicable for both large and small molecule test agents and can be applied to variety of suspension and adherent cell lines including but not limited to tumor cell lines and primary PBMC's.
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