Reagenzien und Instrumente für die Immunologie
Zellbiologie und Molekularbiologie

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Reagenzien und Instrumente für die Immunologie Zellbiologie und Molekularbiologie

Ergebnis Ihrer Suche : 9 Produkt(e) gefunden

Grenzen Sie Ihre Suche ein :

RUOCE / IVD

Unconjugated 8

human 2

Inhibitor/Antagonist/Agonist 6
Primary antibody 2
Service 1

mouse 2

IF 2
IHC 2
WB 2

MGMT/4791 2

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Katalog-Nummer

Beschreibung

Cond.

Preis zzgl. MwSt.

orb1409985-20ug

MGMT (Marker of Suppressor of Mutation and Carcinogenesis) antibody

20ug

orb1409985-100ug

MGMT (Marker of Suppressor of Mutation and Carcinogenesis) antibody

100ug

orb1910729-250mg

Activity of KIN-3248, a next-generation pan-FGFR inhibitor, against acquired FGFR-gatekeeper and molecular-brake drug resistance mutations [[2750709-91-0]]

250mg

orb1910729-1g

Activity of KIN-3248, a next-generation pan-FGFR inhibitor, against acquired FGFR-gatekeeper and molecular-brake drug resistance mutations [[2750709-91-0]]

1g

orb1910729-100mg

Activity of KIN-3248, a next-generation pan-FGFR inhibitor, against acquired FGFR-gatekeeper and molecular-brake drug resistance mutations [[2750709-91-0]]

100mg

orb1910825-1g

MFH290 (MFH-290) is a potent, highly selective, covalent inhibitor of CDK12/13 with IC50 of 25/49 nM.MFH290 forms a covalent bond with Cys-1039 of CDK12, and CDK12-dependent as mutation of Cys-1039 rendered the kinase refractory to MFH290.MFH290 exhibits excellent kinome selectivity, inhibits the phosphorylation of serine-2 in the C-terminal domain (CTD) of RNA-polymerase II (Pol II), and reduces the expression of key DNA damage repair genes.MFH290 restored Pol II CTD phosphorylation and DNA damage repair gene expression AND augments the antiproliferative effect of the PARP inhibitor olaparib. [[2088715-91-5]]

1g

orb1910825-100mg

MFH290 (MFH-290) is a potent, highly selective, covalent inhibitor of CDK12/13 with IC50 of 25/49 nM.MFH290 forms a covalent bond with Cys-1039 of CDK12, and CDK12-dependent as mutation of Cys-1039 rendered the kinase refractory to MFH290.MFH290 exhibits excellent kinome selectivity, inhibits the phosphorylation of serine-2 in the C-terminal domain (CTD) of RNA-polymerase II (Pol II), and reduces the expression of key DNA damage repair genes.MFH290 restored Pol II CTD phosphorylation and DNA damage repair gene expression AND augments the antiproliferative effect of the PARP inhibitor olaparib. [[2088715-91-5]]

100mg

orb1910825-250mg

MFH290 (MFH-290) is a potent, highly selective, covalent inhibitor of CDK12/13 with IC50 of 25/49 nM.MFH290 forms a covalent bond with Cys-1039 of CDK12, and CDK12-dependent as mutation of Cys-1039 rendered the kinase refractory to MFH290.MFH290 exhibits excellent kinome selectivity, inhibits the phosphorylation of serine-2 in the C-terminal domain (CTD) of RNA-polymerase II (Pol II), and reduces the expression of key DNA damage repair genes.MFH290 restored Pol II CTD phosphorylation and DNA damage repair gene expression AND augments the antiproliferative effect of the PARP inhibitor olaparib. [[2088715-91-5]]

250mg

ASC-6012A

CRISPR Custom cell line gene modification; point mutation, samll deletion (<200bp) (normal karyotyping, homozygous); Timeline: 3-5 months

1service

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