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> 7-Dehydrocholesterol [434-16-2]

7-Dehydrocholesterol [434-16-2]

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Cat# 10-3941-1g

Size : 1g

Brand : Focus Biomolecules

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7-Dehydrocholesterol | Ferroptosis inhibitor

CAS:
 434-16-2
Catalog Number:
 10-3941
7-dehydrocholesterol chemical structure Focus Biomolecules

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200 mg$35.00
1 g$50.00
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This product is also available in the following library:
Cholesterol Metabolites

7-Dehydrocholesterol (434-16-2) is an endogenous cholesterol precursor and is photochemically converted to vitamin D3 in the skin.1  It has recently been found to be an endogenous suppressor of ferroptosis and can confer a prosurvival state in cancer cells.2

References/Citations:

  1. MacLaughlin et al. (1982), Spectral character of sunlight modulates photosynthesis pf previtamin D3 and its photoisomers in human skin; Science, 216 1001
  2. Freitas et al. (2024), 7-Dehydrocholesterol is an endogenous suppressor of ferroptosis; Nature, 626 401
CAS:
434-16-2
Catalog Number:
10-3941
Activity:
Endogenous cholesterol precursor/Ferroptosis inhibitor
Chemical Names:
Cholesta-5,7-dien-3ß-ol
Alternate Name:
Provitamin D3
Molecular Weight:
384.65
Molecular Formula:

C27H44O

Solubility:
Soluble in DMSO (5 mg/ml with warming); Ethanol (10 mg/ml)
Physical Properties:
Off-white solid
Purity:

>98% TLC
NMR: (Conforms)

Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

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Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a restocking/refund fee

7-Dehydrocholesterol (434-16-2) is an endogenous cholesterol precursor and is photochemically converted to vitamin D3 in the skin.1  It has recently been found to be an endogenous suppressor of ferroptosis and can confer a prosurvival state in cancer cells.2

References/Citations:

  1. MacLaughlin et al. (1982), Spectral character of sunlight modulates photosynthesis pf previtamin D3 and its photoisomers in human skin; Science, 216 1001
  2. Freitas et al. (2024), 7-Dehydrocholesterol is an endogenous suppressor of ferroptosis; Nature, 626 401