General Info
| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Long-chain-fatty-acid--CoA ligase 1 (210-290 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Gene Symbol: | ACSL1 |
| Gene ID: | 2180 |
| Uniprot ID: | ACSL1_HUMAN |
| Immunogen Region: | 210-290 aa |
| Specificity: | ACSL1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 210-290 |
Description
| Function | Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate. Preferentially activates arachidonate than epoxyeicosatrienoic acids (EETs) or hydroxyeicosatrienoic acids (HETEs). |
| Protein Name | Long-Chain-Fatty-Acid--Coa Ligase 1Acyl-Coa Synthetase 1Acs1Arachidonate--Coa LigaseLong-Chain Acyl-Coa Synthetase 1Lacs 1Long-Chain Acyl-Coa Synthetase 2Lacs 2Long-Chain Fatty Acid-Coa Ligase 2Palmitoyl-Coa Ligase 1Palmitoyl-Coa Ligase 2Phytanate--Coa Ligase |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-2046105Reactome: R-HSA-2046106Reactome: R-HSA-75876 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iii Membrane ProteinPeroxisome MembraneMicrosome MembraneEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Long-Chain-Fatty-Acid--Coa Ligase 1 antibodyAnti-Acyl-Coa Synthetase 1 antibodyAnti-Acs1 antibodyAnti-Arachidonate--Coa Ligase antibodyAnti-Long-Chain Acyl-Coa Synthetase 1 antibodyAnti-Lacs 1 antibodyAnti-Long-Chain Acyl-Coa Synthetase 2 antibodyAnti-Lacs 2 antibodyAnti-Long-Chain Fatty Acid-Coa Ligase 2 antibodyAnti-Palmitoyl-Coa Ligase 1 antibodyAnti-Palmitoyl-Coa Ligase 2 antibodyAnti-Phytanate--Coa Ligase antibodyAnti-ACSL1 antibodyAnti-FACL1 antibodyAnti-FACL2 antibodyAnti-LACS antibodyAnti-LACS1 antibodyAnti-LACS2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance