Reagents and instruments for immunology, cell biology and molecular biology.

Anti-Doc2B Antibody FL490 Conjugate

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Cat# 75-214-FL490

Size : 200uL

Contact local distributor :

Phone : +1 850 650 7790

Brand : Antibodies Incorporated

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Contact local distributor :

Phone : +1 850 650 7790

SKU: 75-214-FL490

Product Details

Target

Doc2b

Target Description

Double C2-like domain-containing protein beta or Doc2b is encoded by the gene DOC2b. Doc2b functions as a calcium sensor which positively regulates soluble NSF attachment receptor (SNARE) dependent fusion of vesicles with membranes. Doc2b binds phospholipids and may act at the priming stage of membrane fusion by modifying membrane curvature to stimulate fusion. Doc2b is expressed in pancreatic cells, endocrine cells and brain, where it is highly expressed in neurons. (Friedrich et al.Neurosci., July 2, 2008 (27):6794 )

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N150/21

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Doc2b

Molecular Weight

45 kDa

Antigen

Fusion protein amino acids 1-216 (N-terminus) of rat Doc2b (accession number P70610) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2939792

Storage

Aliquot and store at -8% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with Doc2a

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Double C2-like domain-containing protein beta (Doc2-beta)

UniProt Details

UniProt (Human): Q14184
UniProt (Immunogen Species): P70610

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