CD44 antibody [IM7] (Biotin)
Cat# GTX19629-125ug
Size : 125ug
Brand : GeneTex
Contact local distributor :
Phone : +1 850 650 7790
![Anti-CD44 antibody [IM7] (Biotin) used in Flow cytometry (FACS). GTX19629](http://www.genetex.com/templates/default/js/lightbox/images/loading.gif "Anti-CD44 antibody [IM7] (Biotin) used in Flow cytometry (FACS). GTX19629")
Host | Rat |
|---|---|
Clonality | Monoclonal |
Clone Name | IM7 |
Isotype | IgG2b |
Application | IHC-Fr, FACS, IP |
Reactivity | Human, Bovine, Cat, Dog, Pig, Horse |
| Package | 125 μg |
Datasheet File View product citations for antibody GTX19629 on CiteAb
APPLICATION
Application Note
FACS: Use 1μg for 10^6 cells. IHC-Fr (acetone fixed): Use at an assay dependent dilution. IP: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.
Calculated MW
82 kDa. ( Note )
Product Note
Recognizes all isoforms of the Pgp-1 cell surface glycoprotein. The CD44 is present on B-cells, monocytes, macrophages and certain subsets of thymocytes and peripheral T-cells. Mice with the Ly-24.1 allotype have high densities of CD44+ T-cells, while Ly-24.2 strains are low expressors.
PROPERTIES
Form
Liquid
Buffer
PBS, 1% BSA
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Immunogen
Unfortunately, this information is considered to be commercially sensitive
Purification
Protein A purified
Conjugation
Biotin
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CD44 molecule (Indian blood group) , CDW44 , CSPG8 , ECMR-III , HCELL , HUTCH-I , IN , LHR , MC56 , MDU2 , MDU3 , MIC4 , Pgp1
Cellular Localization
Cell membrane
Background
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
Database
DATA IMAGES
| | GTX19629 FACS ImageStaining of C57 splenocytes with Anti-Mouse CD44: Biotin (purple histogram) or Rat IgG2b Isotype Control: Biotin (open histogram) followed by UltraAvidin: PE |
Clone Reference
de S? Schiavo Matias G et al. Bioengineered 2022; 13 (2):3551-3565 In vivo biocompatibility analysis of the recellularized canine tracheal scaffolds with canine epithelial and endothelial progenitor cells.
Hendawy H et al. Animals (Basel) 2021; 11 (2) Tissue Harvesting Site Effect on the Canine Adipose Stromal Vascular Fraction Quantity and Quality.
Chae HK et al. VETIMM 2017; S0165-2427 (16):30381-6 Immunomodulatory Effects of Soluble Factors Secreted by Feline Adipose Tissue-derived Mesenchymal Stem Cells.
Lin CW et al. Acta Biomater 2016; cd44-specific nanoparticles for redox-triggered reactive oxygen species production and * release.
REVIEW
Clone Reference
de S? Schiavo Matias G et al. Bioengineered 2022; 13 (2):3551-3565 In vivo biocompatibility analysis of the recellularized canine tracheal scaffolds with canine epithelial and endothelial progenitor cells.
Hendawy H et al. Animals (Basel) 2021; 11 (2) Tissue Harvesting Site Effect on the Canine Adipose Stromal Vascular Fraction Quantity and Quality.
Chae HK et al. VETIMM 2017; S0165-2427 (16):30381-6 Immunomodulatory Effects of Soluble Factors Secreted by Feline Adipose Tissue-derived Mesenchymal Stem Cells.
Lin CW et al. Acta Biomater 2016; cd44-specific nanoparticles for redox-triggered reactive oxygen species production and * release.
| SDS | |
|---|---|
| PBS.pdf | |
| Sodium Azide.pdf | |