CLA Chemiluminescence Substrate

CLA Chemiluminescence Substrate
Catalog number: B2012186
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 225.25 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: CLA-phenyl, 2-Methyl-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Osman AM, Laane C, Hilhorst R. Enhanced sensitivity of Cypridina luciferin analogue (CLA) chemiluminescence for the detection of *O2(-) with non-ionic detergents Luminescence. 2001 Jan-Feb;16(1):45-50.
2: Tan X, Song Z. Human saliva-based quantitative monitoring of clarithromycin by flow injection chemiluminescence analysis: a pharmacokinetic study Appl Biochem Biotechnol. 2014 Feb;172(3):1320-31.
3: Nakano M, Sugioka K, Ushijima Y, Goto T. Chemiluminescence probe with Cypridina luciferin analog, 2-methyl-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one, for estimating the ability of human granulocytes to generate O2- Anal Biochem. 1986 Dec;159(2):363-9.
4: Wang M, Yu SH, Han ZZ. The utility of grey zone testing in improving blood safety Am J Transl Res. 2021 Aug 15;13(8):9771-9777. eCollection 2021.
5: Niu J, Fan J, Wang X, Xiao Y, Xie X, Jiao X, Sun C, Tang B. Simultaneous Fluorescence and Chemiluminescence Turned on by Aggregation-Induced Emission for Real-Time Monitoring of Endogenous Superoxide Anion in Live Cells Anal Chem. 2017 Jul 5;89(13):7210-7215.
6: Stevens A, Lang R, Schabet M, Wiethölter H, Hammann K. Spontaneous chemiluminescence activity of peripheral blood cells during experimental allergic neuritis (EAN) J Neuroimmunol. 1990 Apr;27(1):33-40.
7: Shin JW, Jin SP, Lee JH, Cho S. Analysis of MAST-CLA Results as a Diagnostic Tool in Allergic Skin Diseases Ann Dermatol. 2010 Feb;22(1):35-40.
8: Constable DW, Harris RI, Ganderton MA. Statistical problems in assessing the true value of new in vitro diagnostic tests, with special reference to the chemiluminescent assay (CLA, MAST) J Investig Allergol Clin Immunol. 1991 Jun;1(3):169-78.
9: Münzel T, Afanas’ev IB, Kleschyov AL, Harrison DG. Detection of superoxide in vascular tissue Arterioscler Thromb Vasc Biol. 2002 Nov 1;22(11):1761-8.
10: Yu X, Liu S, Cheng Q, Wei T, Lee S, Zhang D, Siegwart DJ. Lipid-Modified Aminoglycosides for mRNA Delivery to the Liver Adv Healthc Mater. 2020 Apr;9(7):e1901487.

Products Related to CLA Chemiluminescence Substrate can be found at Chemiluminescence