EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (laforin), EPM2, MELF) (MaxLight 550)

Cat# 245789-ML550-100ul

Size : 100ul

Brand : US Biological

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245789-ML550 EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (laforin), EPM2, MELF) (MaxLight 550)

Clone Type
Polyclonal
Host
mouse
Isotype
IgG2a,k
Grade
Purified
Applications
FLISA WB
Accession #
NP_001018051
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze

MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. ||This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq||Applications: |Suitable for use in Western Blot. Other applications not tested.||Recommended Dilution:|Optimal dilutions to be determined by the researcher.||AA Sequence:|GNGPHHDRCCTYNENNLVDGVYCLPIGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIV||Storage and Stability:|Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. ||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Mab|Isotype: IgG2a,k|Clone No: 4A12|Host: mouse|Concentration: As reported|Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550.|Purity: Purified|Immunogen: EPM2A (NP_001018051, 101aa-199aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.|Specificity: Recognizes EPM2A.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
EPM2A (NP_001018051, 101aa-199aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550.
Purity
Purified
Specificity
Recognizes EPM2A.
References
1.A Bioassay for Lafora Disease and Laforin Glucan Phosphatase Activity. Sherwood AR, Johnson MB, Delgado-Escueta AV, Gentry MSClin Biochem. 2013 Sep 6. pii: S0009-9120(13)00395-0. doi: 10.1016/j.clinbiochem.2013.08.016.