HHV DNA polymerase catalytic subunit Antibody
Cat# bs-10489R
Size : 100ul
Brand : Bioss
Contact local distributor :
Phone : +1 850 650 7790
HHV DNA polymerase catalytic subunit Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-10489R |
| Product Name | HHV DNA polymerase catalytic subunit Antibody |
| Applications | WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), ICC |
| Specificity | This antibody will detect both HHV1 and HHV2 DNA polymerase catalytic subunit |
| Reactivity | Virus |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Human herpesvirus 1 DNA polymerase catalytic subunit |
| Immunogen Range | 1131-1235/1235 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Subcellular location | Nucleus |
| Synonyms | DPOL_HHV11; DNA polymerase catalytic subunit; UL30; HHV1gp046. |
| Background | Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein. Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction. Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication. |
| Application Dilution | |
| WB | 1:300-5000 |
| ELISA | 1:500-1000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
| ICC | 1:100-500 |