LAG3 is strongly supported by BioGPS gene expression data to be expressed in K562
10, 000 events was performed.
Datasheets/Manuals
Printable datasheet for anti-LAG3 antibody - OAAB04111
Product Info
Predicted Species Reactivity
Human, Mouse
Product Format
Liquid. PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Application
FC, IHC-P, WB
::
Function: Involved in lymphocyte activation. Binds to HLA class-II antigens. Cellular Location: Membrane; Single-pass type I membrane protein. Tissue Location On cell surface of activated NK and T- lymphocytes.
Reconstitution and Storage
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Immunogen
This LAG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the Central region of human LAG3.
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Predicted Homology Based on Immunogen Sequence
Human, Mouse
Concentration
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Sample Type Confirmation
LAG3 is strongly supported by BioGPS gene expression data to be expressed in K562
Intended Use
For research use only and not for use in diagnostic or therapeutic procedures.
Negative regulation of interleukin-2 biosynthetic process
7
Negative regulation of T cell activation
17
Positive regulation of natural killer cell mediated cytotoxicity
20
Cellular components
Name
# of Products
External side of plasma membrane
261
Integral to membrane
2793
Membrane
2769
Protein function
Name
# of Products
Antigen binding
436
MHC class II protein binding
54
Transmembrane signaling receptor activity
687
What is the species homology for "LAG3 Antibody - middle region (OAAB04111)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".
How long will it take to receive "LAG3 Antibody - middle region (OAAB04111)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
What buffer format is "LAG3 Antibody - middle region (OAAB04111)" provided in?
This item is provided in "Liquid. PBS with 0.09% (W/V) sodium azide. ". Additional format options may be available. For more information please contact info@avivasysbio.com.
What are other names for "LAG3 Antibody - middle region (OAAB04111)"?
This target may also be called "CD223" in publications.
What is the shipping cost for "LAG3 Antibody - middle region (OAAB04111)"?
The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.
What is the guarantee for "LAG3 Antibody - middle region (OAAB04111)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
Can I get bulk pricing for "LAG3 Antibody - middle region (OAAB04111)"?
You can get bulk pricing for this item by going here.
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "57437 Da". Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.
What protocols are available for "LAG3 Antibody - middle region (OAAB04111)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
What are positive controls for "LAG3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What are negative controls for "LAG3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What other proteins interact with "LAG3"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
What biological processes are associated with "LAG3"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
What cellular components are associated with "LAG3"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
What protein functions are associated with "LAG3"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
ELISA Titer: 1:312500 Positive Control: Human heart" data-size="300x300" class="product-image-wrapper cover">
LAG3 Antibody - C-terminal region (ARP59142_P050)
Catalog #: ARP59142_P050
Species Tested: Human
Application: WB
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Phone : +1 850 650 7790