Conjugation | PerCP-Cyanine5.5 |
---|---|
Antigen | CD11b |
Clone | OKM1 |
Isotype | IgG2b, k |
Applications | FC |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Primary/Secondary | Primary |
Immunogen | Human lymph node lymphocytes |
Format | 0.09% sodium azide, 0.2% BSA (w/v), PBS pH 7.2 |
Storage | 2-8°C |
Status | RUO |
Excitation Laser | Blue (488nm) |
CD11b PerCP-Cyanine5.5
Catalog #
Size
Monocyte gated PBMCs stained with CD11b PerCP-Cyanine5.5 (RED); Monocyte gated PBMCs stained with IgG2b PerCP-Cyanine5.5 (BLUE).
Description:
The clone OKM1, a mouse monoclonal antibody, binds with a 165 kDa adhesion glycoprotein present in human cells known as CD11b. CD11b associates with the 95 kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2), and CD50 (ICAM-3).
The clone OKM1, a mouse monoclonal antibody, binds with a 165 kDa adhesion glycoprotein present in human cells known as CD11b. CD11b associates with the 95 kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2), and CD50 (ICAM-3).