Rhein-8-O-β-D-glucopyranoside

Biological Activity

Rhein-8-glucoside calcium, a anthraquinone compound isolated from EtOH extract of Saussurea lappa root. Rhein-8-glucoside calcium is an hPTP1B inhibitor with an IC50 value of 11.5 μM. Rhein-8-glucoside calcium has antibacterial effects.

Chemical Information

Molecular Weight	484.42
Formula	C21H16O11.Ca
CAS Number	113443-70-2
Storage	Powder          -20°C   3 years ;  4°C   2 years In solvent       -80°C   6 months ;  -20°C   1 month

References

[1] Yaochao Zhang, et al. Effects of Rhein-8-O-β-D-glucopyranoside on the Biofilm Formation of Streptococcus mutans

[2] Lan-Sheng Zhang, et al. Rhein-8-O-β-D-glucopyranoside inhibited high glucose-induced apoptosis of human mesangial cells by regulating the lincRNA ANRIL/let-7a/TGF-β1/Smad signaling pathway

[3] Kento Takayama, et al. Rhein 8-O-β-D-Glucopyranoside Elicited the Purgative Action of Daiokanzoto (Da-Huang-Gan-Cao-Tang), Despite Dysbiosis by Ampicillin

[4] Kento Takayama, et al. The influence of rhein 8-O-β-D-glucopyranoside on the purgative action of sennoside A from rhubarb in mice

[5] Cun Zhang, et al. Two new anthraquinone glycosides from the roots of Rheum palmatum