General Info
| Host: | CHO cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | RNase 7-protein was developed from cho cells. For use in research applications. |
| Formulation: | 10 mM Na-acetate, pH 5.0; 150 mM NaCl |
| Purification: | Purified by affinity chromatography and gel-filtration from serum-free CHO growth media. |
| Concentration: | 1.9 mg/ml |
| Storage Instruction: | Store at-70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles. |
Information
| Gene Symbol: | RNASE7 |
| Gene ID: | 84659 |
| Uniprot ID: | RNAS7_HUMAN |
Description
| Function | Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Causes loss of bacterial membrane integrity. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity. |
| Protein Name | Ribonuclease 7Rnase 7Skin-Derived Antimicrobial Protein 2Sap-2 |
| Database Links | Reactome: R-HSA-6803157 |
| Cellular Localisation | SecretedDetected In Urine |
| Alternative Protein Names | Ribonuclease 7 proteinRnase 7 proteinSkin-Derived Antimicrobial Protein 2 proteinSap-2 proteinRNASE7 proteinUNQ2516 proteinPRO6006 protein |
Information sourced from Uniprot.org
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