Sodium citrate (dihydrate) [6132-04-3]
Cat# HY-B1610-500mg
Size : 500mg
Brand : MedChemExpress
Sodium citrate dehydrate (Trisodium citrate dihydrate) is a natural product with oral activity that can be found in citrus fruits. Sodium citrate dehydrate can inhibit the proliferation of tumor cells and induce apoptosis. Sodium citrate dehydrate has antibacterial, anti-tumor and antioxidant activities. Sodium citrate dehydrate can be prepared as a cosolvent or buffer.
For research use only. We do not sell to patients.
Sodium citrate dihydrate Chemical Structure
CAS No. : 6132-04-3
This product is a controlled substance and not for sale in your territory.
Based on 3 publication(s) in Google Scholar
Other Forms of Sodium citrate dihydrate:
- Lithium citrate tetrahydrate In-stock
- Sodium citrate dihydrate, meets USP testing specifications In-stock
- Citric acid trisodium In-stock
- Citric acid In-stock
- Citric acid tripotassium hydrate In-stock
- Sodium citrate dihydrate, United States Pharmacopeia (USP) Reference Standard Get quote
- Sodium citrate dihydrate, for molecular biology Get quote
Description |
Sodium citrate dehydrate (Trisodium citrate dihydrate) is a natural product with oral activity that can be found in citrus fruits. Sodium citrate dehydrate can inhibit the proliferation of tumor cells and induce apoptosis. Sodium citrate dehydrate has antibacterial, anti-tumor and antioxidant activities. Sodium citrate dehydrate can be prepared as a cosolvent or buffer[1][2][3]. |
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IC50 & Target |
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In Vitro |
Sodium citrate dehydrate (100 μM) can enhance the inhibition effect of rosemary acid (RA) on Vibrio bacterial[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability Assay[2]
Apoptosis Analysis[2]
Western Blot Analysis[2]
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In Vivo |
Sodium citrate dehydrate (216, 746 mg/kg, gavage for 16 weeks) can inhibit endoplasmic reticulum stress in rats with chronic renal failure induced by adenine (HY-B0152)[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Clinical Trial |
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Molecular Weight |
294.10 |
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Formula |
C6H9Na3O9 |
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CAS No. |
6132-04-3 |
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Appearance |
Solid |
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Color |
White to off-white |
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SMILES |
O=C(CC(C(O[Na])=O)(O)CC(O[Na])=O)O[Na].O.O |
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Structure Classification |
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Initial Source |
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Shipping | Room temperature in continental US; may vary elsewhere. |
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Storage |
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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Solvent & Solubility |
In Vitro:
H2O : 125 mg/mL (425.03 mM; Need ultrasonic) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
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Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles. * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
For the following dissolution methods, please prepare the working solution directly.
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
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Purity & Documentation |
Purity: ≥98.0% |
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References |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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H2O | 1 mM | 3.4002 mL | 17.0010 mL | 34.0020 mL | 85.0051 mL |
5 mM | 0.6800 mL | 3.4002 mL | 6.8004 mL | 17.0010 mL | |
10 mM | 0.3400 mL | 1.7001 mL | 3.4002 mL | 8.5005 mL | |
15 mM | 0.2267 mL | 1.1334 mL | 2.2668 mL | 5.6670 mL | |
20 mM | 0.1700 mL | 0.8501 mL | 1.7001 mL | 4.2503 mL | |
25 mM | 0.1360 mL | 0.6800 mL | 1.3601 mL | 3.4002 mL | |
30 mM | 0.1133 mL | 0.5667 mL | 1.1334 mL | 2.8335 mL | |
40 mM | 0.0850 mL | 0.4250 mL | 0.8501 mL | 2.1251 mL | |
50 mM | 0.0680 mL | 0.3400 mL | 0.6800 mL | 1.7001 mL | |
60 mM | 0.0567 mL | 0.2834 mL | 0.5667 mL | 1.4168 mL | |
80 mM | 0.0425 mL | 0.2125 mL | 0.4250 mL | 1.0626 mL | |
100 mM | 0.0340 mL | 0.1700 mL | 0.3400 mL | 0.8501 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Sodium citrate dihydrate Related Classifications
- Anti-infection Metabolic Enzyme/Protease Apoptosis
- Bacterial Endogenous Metabolite Apoptosis