Ampicillin [69-53-4]
Cat# HY-B0522-1g
Size : 1g
Brand : MedChemExpress
Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.
For research use only. We do not sell to patients.
Ampicillin Chemical Structure
CAS No. : 69-53-4
This product is a controlled substance and not for sale in your territory.
Based on 37 publication(s) in Google Scholar
Other Forms of Ampicillin:
- Ampicillin sodium In-stock
- Ampicillin trihydrate In-stock
- Ampicillin-d5 In-stock
Description |
Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria. |
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IC50 & Target |
|
||||||||||||
In Vitro |
Ampicillin inhibits the growth of E. coli of swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin was 2.5 uG/mL[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
||||||||||||
In Vivo |
Ampicillin is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig[1]. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood[2]. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
||||||||||||
Clinical Trial |
|
||||||||||||
Molecular Weight |
349.40 |
||||||||||||
Formula |
C16H19N3O4S |
||||||||||||
CAS No. |
69-53-4 |
||||||||||||
Appearance |
Solid |
||||||||||||
Color |
White to off-white |
||||||||||||
SMILES |
OC([C@@H]1N(C2=O)[C@]([C@@H]2NC([C@@H](C3=CC=CC=C3)N)=O)(05)SC1(C)C)=O |
||||||||||||
Shipping | Room temperature in continental US; may vary elsewhere. |
||||||||||||
Storage |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
||||||||||||
Solvent & Solubility |
In Vitro:
0.1 M NaOH : 25 mg/mL (71.55 mM; Need ultrasonic) H2O : 4.9 mg/mL (14.02 mM; ultrasonic and warming and adjust pH to 9 with NaOH and heat to 60°C) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles. * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
|
||||||||||||
Purity & Documentation |
Purity: 99.92% |
||||||||||||
References |
|
Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
---|
H2O / 0.1 M NaOH | 1 mM | 2.8620 mL | 14.3101 mL | 28.6201 mL | 71.5503 mL |
5 mM | 0.5724 mL | 2.8620 mL | 5.7240 mL | 14.3101 mL | |
10 mM | 0.2862 mL | 1.4310 mL | 2.8620 mL | 7.1550 mL | |
0.1 M NaOH | 15 mM | 0.1908 mL | 0.9540 mL | 1.9080 mL | 4.7700 mL |
20 mM | 0.1431 mL | 0.7155 mL | 1.4310 mL | 3.5775 mL | |
25 mM | 0.1145 mL | 0.5724 mL | 1.1448 mL | 2.8620 mL | |
30 mM | 0.0954 mL | 0.4770 mL | 0.9540 mL | 2.3850 mL | |
40 mM | 0.0716 mL | 0.3578 mL | 0.7155 mL | 1.7888 mL | |
50 mM | 0.0572 mL | 0.2862 mL | 0.5724 mL | 1.4310 mL | |
60 mM | 0.0477 mL | 0.2385 mL | 0.4770 mL | 1.1925 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.