Anti-Proton Pump (H,K-ATPase beta subunit) (Mouse) mAb
Cat# D032-3
Size : 100μg
Brand : MBL International
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Phone : +1 850 650 7790
Please Note: MBL International will be shutting down its operations effective December 31, 2024. Distribution of MBL products in the United States will be transferred to Cosmo Bio US on January 1st while European Distributors will remain unchanged. For any US inquiries regarding orders or support during this transition, reach out to Cosmo Bio: https://www.cosmobiousa.com/. For Non-US inquiries reach out to MBL in Japan: https://www.mblbio.com/.
D032-3
Antibody
100 μg
Monoclonal antibody of 100 μg targeting Proton pump (H,K-ATPase β subunit) for IHC, IPP, WB.
| Target | Proton pump |
|---|---|
| Product Type | Antibody |
| Application | IHC, IP, WB |
| Clonality | Monoclonal |
| Conjugate | Unlabeled |
| Isotype | IgG1 |
| Immunogen | Hybridoma, fusion of spleen cells Balb / c nu removal of thymus cells and induce Sp2/0-Ag14 myeloma, autoimmune gastritis / + mouse neonatal |
| Host Species | Mouse |
| Species Reactivity | Human, Bovine, Mouse, Rat |
| Formulation | 100 µg IgG in 100 µl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained. |
| Research Area | Apoptosis |
| Description/Background | Hydrogen-potassium adenosine triphosphatase (H+, K+-ATPase) belongs to a family of P-type cation-transporting ATPases that also includes Ca2+-ATPase and Na+, K+-ATPase. H+, K+ ATPase is responsible for acid secretion into the stomach and catalyzes electroneutral exchange of cytoplasmic hydrogen ions and external potassium ions coupled with ATP hydrolysis. The enzyme is found in gastric parietal cells where it is located in cytoplasmic vesicles or apical plasma membranes of the secretory canaliculus. H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic α subunit and a smaller but heavily glycosylated β subunit. The α subunit of H+, K+-ATPase has 10 transmembrane domains and contains sites for ATP binding and its acylphosphorylation, binding sites of proton pump inhibitors, and sites responsible for ion recognition. |
| Storage Temperature | -20°C |
| Protocols | IHC, IP, WB |
| Clone Number | 2B6 |
| Concentration | 1 mg/ml |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
D032-3
Antibody
100 μg