Human Apolipoprotein C3

Product Description

Human Apolipoprotein C3
Catalog number: B2012266
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 1.0 mg/mL
Supplied as: Liquid
Applications: molecular tool for various biochemical applications
Storage: -20C
Keywords: ApoCIII, ApoC3
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Zewinger S, Reiser J, Jankowski V, Alansary D, Hahm E, Triem S, Klug M, Schunk SJ, Schmit D, Kramann R, Körbel C, Ampofo E, Laschke MW, Selejan SR, Paschen A, Herter T, Schuster S, Silbernagel G, Sester M, Sester U, Aßmann G, Bals R, Kostner G, Jahnen-Dechent W, Menger MD, Rohrer L, März W, Böhm M, Jankowski J, Kopf M, Latz E, Niemeyer BA, Fliser D, Laufs U, Speer T. Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation Nat Immunol. 2020 Jan;21(1):30-41.
2: Chait A. Hypertriglyceridemia Endocrinol Metab Clin North Am. 2022 Sep;51(3):539-555.
3: Tall AR, Thomas DG, Gonzalez-Cabodevilla AG, Goldberg IJ. Addressing dyslipidemic risk beyond LDL-cholesterol J Clin Invest. 2022 Jan 4;132(1):e148559.
4: Burnap SA, Sattler K, Pechlaner R, Duregotti E, Lu R, Theofilatos K, Takov K, Heusch G, Tsimikas S, Fernández-Hernando C, Berry SE, Hall WL, Notdurfter M, Rungger G, Paulweber B, Willeit J, Kiechl S, Levkau B, Mayr M. PCSK9 Activity Is Potentiated Through HDL Binding Circ Res. 2021 Nov 12;129(11):1039-1053.
5: Schunk SJ, Hermann J, Sarakpi T, Triem S, Lellig M, Hahm E, Zewinger S, Schmit D, Becker E, Möllmann J, Lehrke M, Kramann R, Boor P, Lipp P, Laufs U, März W, Reiser J, Jankowski J, Fliser D, Speer T, Jankowski V. Guanidinylated Apolipoprotein C3 (ApoC3) Associates with Kidney and Vascular Injury J Am Soc Nephrol. 2021 Sep 29;32(12):3146-60.
6: Wang H, Huang X, Xu P, Liu X, Zhou Z, Wang F, Li J, Wang Y, Xian X, Liu G, Huang W. Apolipoprotein C3 aggravates diabetic nephropathy in type 1 diabetes by activating the renal TLR2/NF-κB pathway Metabolism. 2021 Jun;119:154740.
7: Harney DJ, Hutchison AT, Hatchwell L, Humphrey SJ, James DE, Hocking S, Heilbronn LK, Larance M. Proteomic Analysis of Human Plasma during Intermittent Fasting J Proteome Res. 2019 May 3;18(5):2228-2240.
8: Su X, Peng D. The exchangeable apolipoproteins in lipid metabolism and obesity Clin Chim Acta. 2020 Apr;503:128-135.
9: Galton DJ. Clarifying complex inheritance: apolipoprotein C3 and atherosclerosis Curr Opin Lipidol. 2017 Aug;28(4):308-312.
10: Heinz P, Boehm BO, Schmidberger J, Kratzer W; EMIL-Study Group. Association of Apolipoprotein C3 Levels and Hepatic Steatosis: A Follow-Up Study Horm Metab Res. 2020 Apr;52(4):236-245.

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