Mdivi-1 [338967-87-6]
Cat# HY-15886-5mg
Size : 5mg
Brand : MedChemExpress
Mdivi-1 is a selective dynamin-related protein 1 (Drp1) inhibitor. Mdivi-1 is a mitochondrial division/mitophagy inhibitor.
For research use only. We do not sell to patients.
Mdivi-1 Chemical Structure
CAS No. : 338967-87-6
This product is a controlled substance and not for sale in your territory.
Based on 145 publication(s) in Google Scholar
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Mdivi-1 purchased from MedChemExpress. Usage Cited in: Vet Microbiol. 2023 May.
- S.aureus-induced reduction of mitochondrial proteins is blocked by Mdivi-1 (20 μM; 2 h) in BMECs.
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Mdivi-1 purchased from MedChemExpress. Usage Cited in: Theranostics. 2019 Feb 28;9(6):1698-1713. [Abstract]
- Western blotting of SDs and markers of podocyte dedifferentiation with the treatment of PA , BBR + PA and Mdivi1+PA.
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Mdivi-1 purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2019 Mar 8;10(3):232. [Abstract]
- HepG2/ADM cells are pretreated with mdivi-1 (10 μM) for 1 h, followed by treatment with B5G1 (6 μM) for another 48 h. Apoptosis-related proteins expression level is detected by western blotting. β-actin was used as a loading control.
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Mdivi-1 purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2019 Mar 8;10(3):232. [Abstract]
- HepG2/ADM cells are pretreated with mdivi-1 (10 μM) for 1 h, followed by treatment with B5G1 (6 μM) for another 24 h. Mitochondrial colocalization with LC3 is detected by immunofluorescence.
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Mdivi-1 purchased from MedChemExpress. Usage Cited in: Brain Res. 2019 May 15;1711:68-76. [Abstract]
- Levels of CytC in cytosol (Cyto-CytC), CytC in mitochondria (Mito- CytC) and cleaved caspase-3 in hippocampus are determined by western blot with the treatment of sham, HIR, MDV or FK506.
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Mdivi-1 purchased from MedChemExpress. Usage Cited in: J Pineal Res. 2018 Sep;65(2):e12491. [Abstract]
- Inhibition of mitochondrial fission with mdivi-1 or Drp1 siRNA suppresses hyperglycemia-induced oxidative stress. Protein expression of Nox4.
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Mdivi-1 purchased from MedChemExpress. Usage Cited in: Transl Res. 2018 Apr;194:68-78. [Abstract]
- Representative western blot analysis of pDrp1-616 and total Drp1 protein expression in the hippocampus (left). Tubulin is used as the loading control. Protein expressions are quantified by western blot band intensity (right).
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Mdivi-1 purchased from MedChemExpress. Usage Cited in: Free Radic Biol Med. 2017 Nov;112:336-349. [Abstract]
- Mdivi-1 administration reduces NF-κB-dependent inflammation. A. Western blot assay and quantitative analysis of Cyto-p65 (A) and Nec-p65 (B) expression. ß-actin and H3 are used as internal controls of cytosolic and nuclear subfractions, respectively.
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Mdivi-1 purchased from MedChemExpress. Usage Cited in: Exp Neurol. 2017 Sep;295:116-124. [Abstract]
- Mdivi-1 treatment inhibits the expression of DRP1, alleviates ROS and reduces the expression of NLRP3 and cleaved caspase-1 at 24 h after SAH. Representative Western blots showing levels of DRP1.