NTRK2m Recombinant, Mouse, aa32-429, His-Tag (BDNF/NT-3 growth factors Receptor, Ntrk2, GP145-TrkB/GP95-TrkB, Tkrb, Trk-B, TrkB)

Cat# 351402-250ug

Size : 250ug

Brand : US Biological

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351402 NTRK2m Recombinant, Mouse, aa32-429, His-Tag (BDNF/NT-3 growth factors Receptor, Ntrk2, GP145-TrkB/GP95-TrkB, Tkrb, Trk-B, TrkB)

Clone Type
Polyclonal
Grade
Highly Purified
Accession #
NP_001020245
Shipping Temp
Blue Ice
Storage Temp
-20°C/-70°C

NTRK2, also known as BDNF/NT-3 growth factors receptor, is a member of the neurotrophic tyrosine receptor kinase family. This protein involves in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, differentiation, and synapse formation and plasticity.||Recombinant protein corresponding to aa32-429 from mouse NTRK2, fused to His-tag at C-terminal expressed in insect cell. ||Molecular Weight: |~45.7kD (409aa)||Amino Acid Sequence:|CPTSCKCSSA RIWCTEPSPG IVAFPRLEPN SVDPENITEI LIANQKRLEI INEDDVEAYV GLRNLTIVDS GLKFVAYKAF LKNSNLRHIN FTRNKLTSLS RRHFRHLDLS DLILTGNPFT CSCDIMWLKT LQETKSSPDT QDLYCLNESS KNMPLANLQI PNCGLPSARL AAPNLTVEEG KSVTLSCSVG GDPLPTLYWD VGNLVSKHMN ETSHTQGSLR ITNISSDDSG KQISCVAENL VGEDQDSVNL TVHFAPTITF LESPTSDHHW CIPFTVRGNP KPALQWFYNG AILNESKYIC TKIHVTNHTE YHGCLQLDNP THMNNGDYTL MAKNEYGKDE RQISAHFMGR PGVDYETNPN YPEVLYEDWT TPTDIGDTTN KSNEIPSTDV ADQSNREHAA ALEHHHHHH||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Applications
Source: Recombinant, insect cell line|Purity: ≥95% (SDS-PAGE). Endotoxin: ≤1EU/1ug (LAL)|Concentration: ~0.5mg/ml |Form: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Form
Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Purity
≥95% (SDS-PAGE). Endotoxin: ≤1EU/1ug (LAL)
References
1. Heldt SA et al., (2014) J. Neurosci., 34:(7)2444-2450. 2. Xiang J et al., (2014) J. Clin. Invest., 124:(1)85-98.