Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Nucleocapsid Protein (NP) Antibody is a Mouse Monoclonal Antibody for the detection of SARS-CoV-2/COVID-19 NP. The SARS-CoV-2 Nucleoprotein (also known as Nucleocapsid Protein or N Protein) is a protein that binds to the RNA in the viral particle. Changes to two amino acids in the nucleoprotein are thought to contribute to the virus’ ability to infect humans; this mutation allows the virus to reduce the binding capability of an HLA-C allele found in many Europeans. The nucleoprotein is the second most-common protein in SARS-CoV-2 targeted by the immune system, after the spike protein.
Research Articles on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Nucleocapsid Protein
| Target | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Nucleocapsid Protein |
| Clonality | Monoclonal |
| Reactivity | Virus |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant SARS-CoV-2 Nucleocapsid protein (Met1-Ala419) |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Buffer | PBS, pH 7.4, containing 0.05% Proclin-300 and 50% glycerol. |
| Specificity | Recognizes SARS-CoV-2 Nucleocapsid protein |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |