Canvax Biotech


Canvax is a leading manufacturer and supplier of the most innovative solutions, kits and R&D Reagents inside Molecular Biology fields. Since its foundation in 2001, Canvax offers reliable, cost-effective and easy-to-use innovative tools for research.

Based in Córdoba (Spain), since its beginning it has focused on R&D of multiplex high throughput platforms (HTS) for Drug discovery and Diagnostic applied biosensors. Over a decade later, Canvax is a worldwide leading expert in GPCR expression in heterologous cells, with important patents and exclusive know-how. Canvax prides itself to be the first company to get an unprecedented milestone that could revolutionize the Diagnostics sector: Canvax established stable high-level expression of odour GPCRs into heterologous cell lines in 2014.

This key milestone, that could be applied in diagnostic, perfume and cosmetic industry, are being employed to obtain a molecular nose, a sensitive and non-invasive diagnostic molecular device for early detection of cancer, as the nose of trained dogs do. Thanks to this project, Canvax was awarded, in 2013, with the largest Public & Private Contract for Pre competitive Technology Development in Spanish history.

 
Lactate dehydrogenase (LDH)

Lactate dehydrogenase (LDH)

 

Cell death or cytotoxicity is typically evaluated by quantifying plasma membrane lesions. The LDH cytotoxicity assay kits provide a quick and simple method for quantifying cytotoxicity based on measuring the activity of lactate dehydrogenase (LDH) released by damaged cells.
In contrast to many other cytoplasmic enzymes that exist in many cells, either in small amounts (alkaline and acid phosphatase for example) or unstable, LDH is a stable cytoplasmic enzyme present in all cells and rapidly released into the cell culture supernatant after damage to the plasma membrane. The LDH activity can be determined by a coupled enzyme reaction: LDH oxidizes the lactate to pyruvate which then reacts with the tetrazolium salt INT to formazanate. The increase in the amount of formazan produced in the culture supernatant is directly related to the increase in the number of lysed cells. The formazan dye is water soluble and can be detected spectrophotometrically at 500 nm.

 

 

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Cat#
Description
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Price Bef. VAT
CA0020
 400assays 
CA0022
 2,000assays