Cell Biologics
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Cell Biologics is a premier company and the first to offer genetically modified and normal mouse primary endothelial cells and other mouse cell types. The production of mouse primary endothelial cells was not economically or technically feasible until the creation of our company- Cell Biologics. The goal of our scientists and staff is to provide you with the best murine primary endothelial cells and other mouse primary cells for your research needs and to give you customized solutions to your specific research problems. While genetically modified mice have proven to be a useful model for many human pathologies, culture of murine normal or genetically modified endothelial cells and other mouse primary cells are extremely beneficial to multidisciplinary, biomedically important, endothelial cell research in the areas of cell adhesion, angiogenesis, gene therapy and drug targeting. Cell Biologics is dedicated to the rapid development of significant basic and clinical research on the endothelium by saving investigators time, money, and laboratory costs in the production of consistent normal and genetically modified cells in a timely and reproducible manner.
Webste : www.cellbiologics.com
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Primary cells
Primary cells are cells taken directly from a tissue or organ and cultured in vitro for a short period of time. Unlike immortalised cells, they do not proliferate indefinitely in culture and are more representative of the physiological state in vivo. They are sensitive to their environment and can be more difficult to maintain in culture due to their senescence phenomenon, which means that they have a limited number of passages. They are also more difficult to transfect, i.e. to introduce foreign nucleic acids into their cells. Primary cells can be used to study the cellular and molecular mechanisms involved in various biological processes and are often used as in vitro models to better understand how cells function in vivo. They include a wide variety of cell types, such as neurons, stem cells, endothelial cells, immune cells and fibroblasts, and are essential for many research studies in cell and molecular biology. Primary cells are different from cell lines, which are homogeneous populations of cells that are stable after successive mitoses and theoretically have an unlimited capacity to divide.
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