Anti-Vimentin CE/IVD for IHC - Dermopathology

Anti-Vimentin CE/IVD for IHC - Dermopathology

 

Vimentin is the most common member of intermediate filament (IF) family and one of the main components in cytoskeleton structure. It is expressed during cell development and differentiation in variety of mescencymal cells and cell types derived from the mesoderm. Vimentin is essential in the role of cell integrity and cytoskeletal stability. The reorganization of vimentin, similar to all IF proteins, occurs during different stages of the cell cycle and cell signaling by a site-specific phosphorylation (serine and threonine residues). In particular, p21-activated kinase (PAK) phosphorylates at Ser25, Ser38, Ser50, Ser65 and Ser72 which induces vimentin specific reorganization. During cytokinesis, vimentin is regulated by Rho-kinase (ROCK) and Aurora B through phosphorylation at Ser38 and Ser72. Also, coordinated by ROCK and Aurora B, Plk1 induced phosphorylation at Ser82 plays an important role in vimentin segregation. Vimentin labels mesenchymal cells. In combination with a panel of antibodies, it is used to identify tumor with mesenchymal origin and malignant melanoma. Additionally, vimentin is a useful control marker for proper tissue processing.

 

 

 

Colon section
Tonsil section

 

Search result : 2709 product found

Refine your search :

RUOCE / IVD
  • Unconjugated 2329
  • FITC 47
  • PE 22
  • APC 12
  • FITC/PE 2
  • PerCp 1
  • human 2201
  • rat 83
  • mouse 68
  • cow 62
  • monkey 62
  • chicken 53
  • pig 41
  • rabbit 41
  • dog 23
  • cat 22
  • horse 10
  • hamster 5
  • virus 5
  • mouse 1791
  • rabbit 493
  • human 8
  • rat 3
  • Primary antibody
  • IHC 2490
  • FC 107
  • WB 39
  • ICC 28
  • ELISA 10
  • IF 8
  • ISH 6
  • IP 2
  • Microscopy 1
  • Polyclonal 317
  • V9 14
  • 4C4.9 13
  • E29 12
  • 100/D5 11
  • 1A4 11
  • A53-B/A2.26 11
  • AE1 11
  • DF-T1 11
  • 124 10
  • 1F8 10
  • 2F11 10
  • 34bE12 10
  • 45M1 10
  • 8G7G3/1 10
  • Ber-H2 10
  • NK-1 10
  • 4C7 9
  • H-5 9
  • HHF35 9
  • HMB45 9
  • HO36-1.1 9
  • L26 9
  • SP3 9
  • AIF1/1909 8
  • D33 8
  • JC/70A 8
  • PC10 8
  • 2667 7
  • 6847R 7
  • CBC.37.80 7
  • JC2 7
  • LN2 7
  • T311 7
  • 13H4 6
  • 156-3C11 6
  • 1D4 6
  • 405-9A11 6
  • 55k-2 6
  • 57P06 6
  • 6F-H2 6
  • 6H2.1 6
  • 9 E10 6
  • AE1+AE3 6
  • AE3 6
  • BA-4 6
  • C241:5:1:4 6
  • CALP 6
  • D2-40 6
  • DBM15.28 6
  • F7.2.38 6
  • GA5 6
  • PASE/4LJ 6
  • hHCD 6
  • 121SLE 5
  • 123C3 5
  • 123C3.D5 5
  • 144B 5
  • 151 5
  • 158-4D3 5
  • 1B12 5
  • 20B7 5
  • 2121 5
  • 31G7 5
  • 35bH11 5
  • 361 5
  • 3E6 5
  • 3F6 5
  • 44 5
  • 4A4 5
  • 5.2F 5
  • 54/F6 5
  • 56C6 5
  • 59A5 5
  • 5C5 5
  • 5D3 5
  • 66.4.C2 5
  • 6E3 5
  • 6F11 5
  • 8F1 5
  • A-12 5
  • A-8 5
  • A103 5
  • AA1 5
  • AC-1A1 5
  • AE-3 5
  • AE1 & AE3 5
  • AE1+AE3+5D3 5
  • AH26 5
  • ALP/870 5
  • AR 441 5
  • ASTRO/789 5
  • AU1 5
  • B-A38 5
  • B72.3 5
  • BCL6/2497R 5
  • BP53-12 5
  • D-5 5
  • DBM15.75 5
  • DBR16.1 5
APPLY FILTERS
REINITIALIZE