![Human monomers](https://www.clinisciences.com/en/upload/ombre-human-sqqvmy.jpg)
Human monomers
T lymphocytes play a central role in immune system function.
Biotinylated MHC monomers, the building blocks of MHC tetramers, are now available for tetramer construction flexibility and novel applications.
The Biotinylated Class I MHC/peptide complex can be used in research studies involving CD8+ antigen-specific T cells. The Biotinylated Class II MHC/peptide complex can be used in research studies involving CD4+ antigen-specific T cells
![](/upload/monomer-3-hzzdgw.jpg)
![](/upload/monomer-1-hmmk6p.jpg)
Biotinylated MHC Class I monomer is composed of a particular peptide in combination with a particular HLA class I allele that has been biotinylated at the c-terminus of the heavy chain extracellular domain.
![](/upload/monomer-2-nenkaf.jpg)
Biotinylated MHC class II monomer is composed of a particular peptide in combination with a particular HLA class II allele that has been biotinylated at the c-terminus of the beta chain extracellular domain.