qPCR for hematology

Real-time quantitative PCR is used for diagnosis in various fields such as infectious diseases, hematology and oncology.

In hematology, quantitative PCR can detect mutations of certain genes recognized to play a role in different pathologies. The 2 most sought after pathologies studied in real-time quantitative PCR are thrombophilia and hemochromatosis.

Hemochromatosis is a disease that results in an increase in the digestive absorption of iron. Symptoms are caused by excessive iron deposited in several organs of the body.

Thrombophilia is the state of patients who have a particular predisposition to thrombosis. Some complications of pregnancy can also be part of thrombophilia. The factor V Leiden mutation causes thrombophilia, an increased tendency to form abnormal blood clots in the blood vessels. This mutation has been observed in patients with idiopathic thrombotic manifestation.