NeoSpin
Description
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Applications
- Desalting, diafiltration or changing of buffers
- Concentration and purification of biological samples, including antigens, antibodies, enzymes, nucleic acids (single or double strain DNA/RNA samples), microorganisms, and eluates.
- Purification of macromolecular components from tissue culture extracts or cell lysates
- Removal of primers, ligation or molecular markers from the reaction mixture, removal of proteins prior to HPLC.
Characteristic
- All materials are confirming to USP Class VI . In total, five molecular weight cut-off
- (MWCO) options are available, meeting the needs of filtering molecules in different sizes.
- The filter is structurally designed with a high-performance vertical single- (0.5 mL)/double-sided (5 mL & 15 mL) PES filtration membrane, featuring a larger effective filtration area and a higher flow rate.
- The 0.5 mL and 15 mL tubes are provided with supports, improving the stability of the structure, supporting a higher centrifugal speed, and reducing the filtration time.
- The protein recovery is increased to over 80%.
- There is a printed scale and a white area for writing on the tube, facilitating the identification and marking.
- DNase-free, RNase-free, non-pyrogenic
*The products are strictly controlled in accordance with ISO 13485 and ISO 9001 standards, and undergo strict leak-proof and chemical compatibility tests to ensure quality.
Dead stop
- Avoid spinning to dryness: The process does not require complete drying through spinning.
- Predictable concentration factor: Provides a reliable and predictable concentration factor.
- No need for calibration: No calibration is necessary when running multiple samples in parallel.
- Vertical membranes: The membranes are aligned with the filtrate instead of being perpendicular, leading to fewer clogs, reduced waste, and faster filtration.
- Single-step concentration: Capable of achieving 25- to 80-fold concentration in a single step.
Reliable
- Spin precious samples confidently: The unit allows for spinning precious samples with confidence.
- Robust and sleek design: The unit is designed to be sturdy and aesthetically pleasing.
- Leakage prevention: The unit is designed to prevent leakage, ensuring the integrity of the samples.
- Neutrally charged ultrafiltration membrane: The membrane has a neutral charge, resulting in low binding properties that enhance flux (filtration rate) and sample recovery.
- Excellent chemical resistance: The membrane exhibits high resistance to chemical substances, ensuring compatibility with a wide range of samples and solvents.
- Very low extractable: The membrane has minimal leaching of substances, ensuring that the filtered samples are not contaminated with unwanted compounds.
Temperature range: -20°C to +50°C
Autoclavability:
- No
Processing of protein solutions containing biomolecules (albumin, mAbs, lgG, lgM, hormones, growth factors, etc.)
• Acetic Acid (>25%) • Acetonitrile (>30%) • Aliphatic & aromatic esters • Amines • Ammonium hydroxide (>5%) • Aromatic & chlorinated hydrocarbons |
• Butyl acetate (>40%) • Dimethyl acetamide (DMAC) (>30%) • Ethers • Hydrochloric acid (>0.5 Nat 50°C) • Isopropyl Alcohol (> 25%) • Ketone • Methylene chloride (>1%) |
• Methyl ethyl ketone (>1%) • Phosphoric acid (>1 N) • Sodium deoxycholate (>5%) • Sodium hydroxide (>0.5N at 50°C) • Sodium hypochlorite (>0.04%) |
• Tetrahydrofuran (>5%) • Toluene (>1%) |
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