Anti-p63 (clone DBR16.1) Antibody
Rabbit monoclonal antibody
The p63 antibody co-staining with p504s and CK HMW (34βE12) is useful in detection of prostatic adenocarcinomas.
p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate.
p63 has also been shown to be a sensitive marker for Lung Squamous Cell Carcinoma (SqCC), with a sensitivity of ~90%. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.
Why detect p63?
- Useful marker in Prostate Cancer:
- Highly specific to Squamous Cell Carcinoma
- Differiates benign prostate lesions from Prostatic Carcinoma
- p 63 expression in Breast Cancer is highly sensitive and specific marker of metaplasic carcinoma
 Formalin fixed paraffin embedded human Prostate Carcinoma tissue stained with p63 antibody.
|
Clone | DBR16.1 |
| Isotype | Rabbit IgG | |
| Species | Human | |
| Application | IHC | |
| Cellular Localization | Nuclear | |
| Positive Control | Prostate |
| Products | Volume | Format | Cat# |
| Anticorps Anti-p63 de lapin | 0,5 ml | Concentrated | RMAB086R-0.5 |
| 1 ml | RMAB086R-1 | ||
| 6 ml | Ready-to-use | RMPD086R-6 | |
| 25 ml | RMPD086R-25 | ||
| 100 ml | RMPD086R-100 |
Medical devices for in vitro diagnostic. Read the instructions for use carefully.