AG Scientific
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AG Scientific specializes in secondary metabolites derived from fermentation. Most of their products are antibiotics for gene selection, but the catalog also includes antimicrobial, antifungal, anti-cancer, antiviral, antiparasitic and immunosuppressive reagents.
Antibiotics:
AG Scientific, Inc. has developed a series of antibiotic screening agents, including Blasticidin S, G-418, Puromycin, Gentamycin, Kanamycin, Ampicillin, Streptomycin, Carbenicillin.
More recently, AG Scientific has partnered with pharmaceutical customers using CRISPR technology.
Anti-cancer:
The catalog includes secondary metabolites in the field of cancer such as rapamycin, FK-506, cyclosporine A.
Website : www.agscientific.com
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Aristolochic Acid
Aristolochic acid, inherent in the Aristolochiaceae plant family, stands as a subject of profound interest in immunology, cell biology, and molecular biology. This nitrophenanthrene carboxylic acid, encompassing variants such as aristolochic acid I and II, possesses a distinctive chemical structure that intertwines with intricate biological processes.
In immunology, research delves into the compound's potential immunomodulatory effects, shedding light on its role in endosomal acidification and immune cell activation. Concurrently, in cell biology, aristolochic acid's impact on intracellular pH dynamics, enzymatic activities, and membrane transport contributes to the understanding of cellular homeostasis.
At the molecular level, aristolochic acid’s unique structure influences nucleic acids and proteins, unveiling its significance in DNA replication, transcription, and translation. Scientific endeavors, guided by meticulous analytical techniques, aim to unravel the molecular mechanisms underpinning its actions.
Recognizing the dual nature of aristolochic acid, from historical applications in traditional medicine to contemporary health concerns, this article navigates through its complexities. The synthesis of immunological, cellular, and molecular perspectives underscores the compound’s pivotal role in the intricate landscape of biological research.