GLYcoDiag
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GLYcoDiag is a research and development company specialized in glycosciences which provides services and products for the fields of health (biomarkers, therapeutic recombinant glycoproteins, vaccines), cosmetics (active ingredients, design and mechanisms of “glyco-actives”) and environment (biofilms, waste water).
Since 2015, GLYcoDiag develop its own range of reagents and kits for research uses:
Natural and recombinant lectins
Neoglycoproteins and neoglycoclusters
LEctPROFILE® gels, CarbPROFILE gels LEctPROFILE® kits (lectin based kits intended for ligands screening / comparison / detection) Website : www.glycodiag.com
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Glycine Max Lectine (SBA)
Glycine max lectin is isolated from soy bean (Soy bean
agglutinin, SBA) and purified by affinity chromatography. The molecular weight
of the lectin is 120 kDa, it consists of four identical subunits of 30 kDa each
and it displays carbohydrate binding specifity for N-acetyl-D-galactosamine and
galactopyranosyl residues of glycoproteins. Soybean lectin (Glycine Max) is one
of lectins that specifically binds tobeta N-acetyl glucosamine, galactose and
mannose sugar residues.
SBA has specificity for blood groups A1, A2 and B. The
lectin interacts better with neuramidase-treated cells than with untreated
cells. It has selective affinity for lymphocytes and human CD34+ hematopoietic
stem cells. Immobilized conjugates of SBA are therefore important tools for
removing T-cells in bone marrow transplantation.
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