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Amine Oxides
An amine oxide, also known as amine-N-oxide and N-oxide, is a chemical compound that contains the functional group R3N+–O−, an N–O bond with three additional hydrogen and/or hydrocarbon side chains attached to N.
Amine oxides are used as protecting group for amines and as chemical intermediates. Long-chain alkyl amine oxides are used as nonionic surfactants and foam stabilizers.
Amine oxides are highly polar molecules and have a polarity close to that of quaternary ammonium salts. Small amine oxides are very hydrophilic and have an excellent water solubility and a very poor solubility in most organic solvents.
Amine oxides are weak bases with a pKa of around 4.5 that form R3N+–OH, cationic hydroxylamines, upon protonation at a pH below their pKa.
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NB-42-112511-100mg
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