Chondrex
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Chondrex, Inc. manufactures products for pre-clinical autoimmune and inflammatory disease research: reagents to induce experimental models of arthritis, allergic asthma, colitis, sepsis and nephritis, as well as products (antibodies, ELISAs and other assays) to analyse these models and any treatments applied to them.
With 20+ years of experience in purifying collagen for the Collagen-Induced Arthritis model, we are also experts in all things collagen related. We offer many different species and types of purified collagen intended for in vivo and in vitro applications, as well as assay kits to quantify collagen levels in tissue and cell culture samples.
Website: www.chondrex.com
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![Primary Antibodies](https://www.clinisciences.com/en/upload/thumbs/anticorps-primaire-ushe-JArHkFgJ-6055fb.jpg)
Primary Antibodies
An antibody is a glycoprotein or immunoglobulin that binds to an antigen (or part of the antigen called an epitope), this combination makes it possible to induce an immunological reaction against an external agent. An antibody is composed of constant and variable domains. The variable domains constitute the site of binding to the antigen or paratope.
Antibodies are an important tool for the study and detection of many mechanisms and pathologies.
Antibodies are produced naturally by organisms during an immune reaction but antibodies can be produced for use in research or diagnosis. They are then separated into two groups: primary and secondary antibodies. Primary antibodies recognize a specific protein or biomolecule of interest. These primary antibodies are monoclonal or polyclonal antibodies produced in different species such as mice, rats, rabbits ... Monoclonal and polyclonal antibodies have their own advantages and disadvantages that must be considered before choosing a primary antibody.