bioWORLD
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bioWORLD is a global leader in manufacturing and supplying a wide range of products for life science research. With over 25 years of experience, they have focused on providing quality products and excellent customer service. Their diverse customer base includes hospitals, public health institutions, commercial laboratories, biotechnology companies, pharmaceutical firms, universities, and research institutions. Website : www.bio-world.com
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![Lotus tetragonolobus Lectin (LTL)](https://www.clinisciences.com/en/upload/thumbs/lotus-tetragonolobus-lectin-ltl-rt3y6x-534a7e.png)
Lotus tetragonolobus Lectin (LTL)
Lotus tetragonolobus lectin (LTL) is isolated from lotus seeds and is composed of 240 amino acid residues. LTL is a glycoprotein with a molecular weight of 107 kDa and consists of four subunits. This lectin has different isoelectric points of pH 7.3, 7.6, 7.9, 8.2 and a carbohydrate specificity toward α-linked L-fucose containing oligosaccharides, it is most inhibited by L-fucose. Although many of the binding properties of Lotus lectin are similar to those of Ulex europaeus lectin I, the binding affinities and some specificities for oligosaccharides are markedly different between these fucose-specific lectins.
LTL is a fucose-binding anti-H(O) lectin. Reports show that a minimum hemagglutinating dose of 3.3 µg/ml of the purified lectin against neuraminidase-treated human O erythrocytes, 26.4 µg/ml against B erythrocytes, and 105.6 µg/ml against A erythrocytes. Transitional cell carcinoma of the human urinary bladder tend to metastasize when it strongly expresses binding sites for LTL.
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RUOCE / IVD
- Agarose 5
- TRITC 3
- Beads 2
- Biotin 2
- Cy5 2
- DyLight 488 2
- FITC 2
- AP 1
- Cy3 1
- Ferritin 1
- Gold 1
- HRP 1
- Texas Red® 1
- Lectins
- plant 26
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