Cell Biologics
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Cell Biologics is a premier company and the first to offer genetically modified and normal mouse primary endothelial cells and other mouse cell types. The production of mouse primary endothelial cells was not economically or technically feasible until the creation of our company- Cell Biologics. The goal of our scientists and staff is to provide you with the best murine primary endothelial cells and other mouse primary cells for your research needs and to give you customized solutions to your specific research problems. While genetically modified mice have proven to be a useful model for many human pathologies, culture of murine normal or genetically modified endothelial cells and other mouse primary cells are extremely beneficial to multidisciplinary, biomedically important, endothelial cell research in the areas of cell adhesion, angiogenesis, gene therapy and drug targeting. Cell Biologics is dedicated to the rapid development of significant basic and clinical research on the endothelium by saving investigators time, money, and laboratory costs in the production of consistent normal and genetically modified cells in a timely and reproducible manner.
Webste : www.cellbiologics.com
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Human primary cells
Primary cells are cells that have been isolated directly from a living tissue or organ. They are differentiated cells that mimic the physiological state of cells in vivo and are expected to maintain their in vivo functions under optimal conditions for a short period of time. Cells that can be isolated and cultured in vitro undergo a limited number of cell divisions before entering senescence. This limited lifespan is one of the major limitations of using primary cells. With the exception of stem and progenitor cell populations, the majority of primary cells are terminally differentiated cells of a very specific type and high level of function.
Primary cell models are well established, relatively easy and inexpensive to use, and offer several key advantages over the use of tissue sections. The main advantage of this model is that primary cells retain functions and phenotypes close to those of tissues/organs in vivo, and the effect of drugs/toxins can be studied on isolated primary cells at the cellular level.
