Cell Biologics
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Cell Biologics is a premier company and the first to offer genetically modified and normal mouse primary endothelial cells and other mouse cell types. The production of mouse primary endothelial cells was not economically or technically feasible until the creation of our company- Cell Biologics. The goal of our scientists and staff is to provide you with the best murine primary endothelial cells and other mouse primary cells for your research needs and to give you customized solutions to your specific research problems. While genetically modified mice have proven to be a useful model for many human pathologies, culture of murine normal or genetically modified endothelial cells and other mouse primary cells are extremely beneficial to multidisciplinary, biomedically important, endothelial cell research in the areas of cell adhesion, angiogenesis, gene therapy and drug targeting. Cell Biologics is dedicated to the rapid development of significant basic and clinical research on the endothelium by saving investigators time, money, and laboratory costs in the production of consistent normal and genetically modified cells in a timely and reproducible manner.
Webste : www.cellbiologics.com
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![Human Skeletal muscle cells](https://www.clinisciences.com/en/upload/thumbs/bandeau3-trvt59ge-3QGwasXD-ffbb89.png)
Human Skeletal muscle cells
Skeletal muscle cells, one of the largest cell types in the body, are multinucleated cells formed by the fusion of myoblasts. Skeletal muscle regeneration is a complex process. When skeletal muscle is injured, quiescent resident myoblasts called satellite cells are activated to proliferate, migrate, and differentiate. Various cellular signaling pathways, such as phosphatidylinositol 3-kinase, calcineurin, Janus kinase 2/signal transducer and activator of transcription 3 (STAT3), and mitogen-activated protein kinase (MAPK) have been suggested to play an important role in skeletal muscle growth. Insulin-stimulated glucose transport in cultured human skeletal muscle cells is mediated by GLUT4 and heparan sulfate proteoglycan is involved in skeletal muscle differentiation. The fusion of mononucleated cells to form multinucleated myotubes is a central event in skeletal muscle development. Controlling the onset and progression of this process is a complex set of interactions between myoblasts and their environment. Skeletal muscle cell culture is a useful model for studying the process of cell differentiation.
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