Adrenergic Receptor Beta 2

Cat# 589934-100ug

Size : 100ug

Brand : US Biological

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589934 Adrenergic Receptor Beta 2

Clone Type
Polyclonal
Host
rabbit
Source
mouse
Swiss Prot
P18762
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Eq Fe Gp Hm Hu Mc Mo Rt
Shipping Temp
Blue Ice
Storage Temp
-20°C

Adrenergic receptors mediate the hormone and neurotransmitter functions of adrenaline and noradrenaline. Adrenoreceptors function in peripheral tissues and the central nervous system to regulate numerous vascular, metabolic, and neurological functions, and are the target for many therapeutically relevant drugs including those for the treatment of hypertension, asthma, benign prostatic hypertrophy, and depression. Adrenoreceptors are classified by three types and multiple subclasses (alpha1A,1B,1D; alpha2A,2B,2C; and beta1,2,3) based on pharmacological and molecular characteristics.||Applications: |Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.||Recommended Dilution:|Optimal dilutions to be determined by the researcher.||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: mouse|Concentration: As Reported |Form: Supplied as a liquid in PBS, 0.01% sodium azide, 50% glycerol.|Purity: Purified by immunoaffinity chromatography.|Immunogen: Synthetic peptide corresponding to mouse adrenergic receptor Beta 2 at N-terminal. Species sequence homology: chimpanzee, orangutan, tamarin monkey, gorilla, rhesus macaque, equine, hamster, guinea pig, wild boar, feline.|Specificity: Recognizes mouse adrenergic receptor Beta 2. Species Crossreactivity: human and rat||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Synthetic peptide corresponding to mouse adrenergic receptor Beta 2 at N-terminal. Species sequence homology: chimpanzee, orangutan, tamarin monkey, gorilla, rhesus macaque, equine, hamster, guinea pig, wild boar, feline.
Form
Supplied as a liquid in PBS, 0.01% sodium azide, 50% glycerol.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes mouse adrenergic receptor Beta 2. Species Crossreactivity: human and rat
References
1. Generation of G protein-coupled receptor antibodies differentially sensitive to conformational states: A.S. Heimann, et al.; PloS One 12, e0187306 (2017), 2.|Conformation state-sensitive antibodies to G-protein-coupled receptors: A. Gupta, et al.; J. Biol. Chem. 282, 5116 (2007), Application(s): ELISA, Abstract; Full Text