Background

WC1 molecules are transmembrane glycoproteins belonging to the scavenger receptor cysteine-rich family and uniquely expressed on gamma/delta T cells. Gamma delta T cells (γδ T cells) are T cells that have a distinctive T-cell receptor (TCR) on their surface. Most T cells are αβ (alpha beta) T cells with TCR composed of two glycoprotein chains called α (alpha) and β (beta) TCR chains. In contrast, gamma delta (γδ) T cells have a TCR that is made up of one γ (gamma) chain and one δ (delta) chain.

Specifications

Clone - CACTB32A

Isotype - IgG1

Host - Mouse

Known Reactivity - Bison, Bovine, Caprine, Ovine, Water Buffalo

Purification - Anti-bovine WC1+ γδ T cell (WC1-N3 epitope) monoclonal antibody, clone CACTB32A, was produced in ascites fluid, clarified by filtration through a 0.2 micrometer filter.

Application

Flow Cytometry - Flow cytometric profile obtained with ovine leukocytes.