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> Anti-CD45/Ptprc antibody (Clone: 30-F11) {PercP}

Anti-CD45/Ptprc antibody (Clone: 30-F11) {PercP}

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Cat# NB-22-61397-25

Size : 25ug

Brand : Neo Biotech

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Phone : +1 850 650 7790

  • C57BL/6 murine splenocytes were stained with Anti-CD45 antibody [Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained splenocytes (empty black histogram) were used as control.

General Info

Host: Rat
Applications: FC
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Rat monoclonal antibody anti-Receptor-type tyrosine-protein phosphatase C is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: 30-F11
Conjugation: PercP
Isotype: IgG2bk
Formulation: PBS with 0.05% Proclin300, 1% BSA
Concentration: 0.2 mg/mL
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.

Information

Gene Symbol: Ptprc
Gene ID: 19264
Uniprot ID: PTPRC_MOUSE

Description

Post Translational Modifications Heavily N- and O-glycosylated.
Function Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
Protein Name Receptor-Type Tyrosine-Protein Phosphatase C
Leukocyte Common Antigen
L-Ca
Lymphocyte Antigen 5
Ly-5
T200
Cd Antigen Cd45
Database Links Reactome: R-MMU-202427
Reactome: -MMU-416700
Reactome: -MMU-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Membrane Raft
Colocalized With Dpp4 In Membrane Rafts
Alternative Antibody Names Anti-Receptor-Type Tyrosine-Protein Phosphatase C antibody
Anti-Leukocyte Common Antigen antibody
Anti-L-Ca antibody
Anti-Lymphocyte Antigen 5 antibody
Anti-Ly-5 antibody
Anti-T200 antibody
Anti-Cd Antigen Cd45 antibody
Anti-Ptprc antibody
Anti-Ly-5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance