Reagents and instruments for immunology, cell biology and molecular biology.

Anti-Iduna/RNF146 Antibody FL550 Conjugate

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Cat# 75-233-FL550

Size : 200uL

Contact local distributor :

Phone : +1 850 650 7790

Brand : Antibodies Incorporated

Contact local distributor :

Phone : +1 850 650 7790

Our Anti-Iduna/RNF146 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N201/35. It detects mouse and rat Iduna/RNF146, and is purified by Protein A chromatography. It is great for use in ICC.

Species Reactivity

Mouse, Rat

Applications

ICC

Host Species

Mouse

Available Conjugates

Unconjugated

490

594

650

Data Sheet

SKU: 75-233-FL550

Product Details

Target

Iduna/RNF146

Target Description

E3 ubiquitin-protein ligase RNF146, RING finger protein 146 or Iduna is encoded by the gene RNF146. Iduna is a ubiquitin protein ligase that is involved in ubiquitination and degradation. It is thought to be involved with diverse processes including DNA repair, activation of the Wnt signaling pathway, protection from DNA damage induced cell death. Iduna is found in many tissues including brain, heart, spleen, kidney and liver.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N201/35

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

Rnf146

Molecular Weight

40 kDa

Antigen

Fusion protein amino acids 1-359 (full-length) of mouse Iduna (accession number Q9CZW6) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2939849

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

E3 ubiquitin-protein ligase RNF146 (EC 2.3.2.27) (Iduna) (RING finger protein 146) (RING-type E3 ubiquitin transferase RNF146)

UniProt Details

UniProt (Human): Q9NTX7
UniProt (Immunogen Species): Q9CZW6

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