BCA-1, Recombinant, Mouse Ligand 13 , C-X-C Motif Chemokine 13, CXCL13, CXC Chemokine BLC, Small Inducible Cytokine B Subfamily Member 13, Small Inducible Cytokine B13, SCYB13)

BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor, CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes, and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes.||Recombinant mouse BLC is a 9.5kD protein containing 88 amino acid residues, expressed in E. coli, including the four highly conserved cysteine residues present in CXC chemokines.||Amino Acid Sequence: |ILEAHYTNLK CRCSGVISTV VGLNIIDRIQ VTPPGNGCPK TEVVIWTKMK KVICVNPRAK WLQRLLRHVQ SKSLSSTPQA PVSKRRAA||Biological Activity: |Determined by its ability to chemoattract human B cells.||Storage and Stability: |Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. For long term storage add 0.1% HSA or BSA. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.