CD90/THY-1, Recombinant, Human, Fc-Tag

Thy-1 membrane glycoprotein also known as Thy-1 antigen, CD90 and THY1 is a cell membrane protein which contains 1Ig-like V-type (immunoglobulin-like) domain. It is a glycophosphatidylinositol-linked glycoprotein expressed on the surface of neurons, thymocytes, subsets of fibroblasts, endothelial cells, mesangial cells and some hematopoietic cells. It has been identified on a variety of stem cells and at varying levels in non-lymphoid tissues such as on fibroblasts, brain cells and activated endothelial cells. Thy-1 is evolutionarily conserved, developmentally regulated, and often has dramatic effects on cell phenotype. Thy-1 is a 25-37kD glycosylphosphatidylinositol (GPI)-anchored protein involved in |T-cell activation, neurite outgrowth, apoptosis, tumor suppression, wound healing and fibrosis. To mediate these diverse effects, Thy-1 participates in multiple signaling cascades. Thy-1 is an important regulator of cell-cell and cell-matrix interactions, with important roles in nerve regeneration, metastasis, inflammation, and fibrosis.||Source:|Recombinant protein corresponding to Met1-Cys130 from human CD90/THY-1 fused to hFc-Tag at C-terminal, expressed in HEK293 Cells.||Molecular Weight:|~39.3kD||Storage and Stability:|Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.