Cell Counting Kit-8
Cat# M4839-500
Size : 500Tests/5mL
Brand : AbMole Bioscience
Contact local distributor :
Phone : +1 850 650 7790
Intended Use
Cell Counting Kit-8 (CCK-8) allows sensitive colorimetric assays for the determination of cell viability in cell proliferation and cytotoxicity assays.
General Description
CCK solution is a one-bottle solution; no pre-mixing of components is required. CCK, being nonradioactive, allows sensitive colorimetric assays for the determination of the number of viable cells in cell proliferation and cytotoxicity assays. WSTS* is reduced by dehydrogenases in cells to give an orange colored product (formazan), which is soluble in tissue culture medium. The amount of formazan dye generated by dehydrogenases in cells is directly proportional to the number of living cells.
Comparison between CCK method and MTT method:
| Source | Med Sci Monit (2018 Oct). Figure 2. Cell Counting Kit-8 (Abmole Bioscience, USA) | |
| Method | Cell viability assay | |
| Cell Lines | colon cancer cells | |
| Concentrations | 10 nmol/L | |
| Incubation Time | 1 h | |
| Results | Then, CCK8 assay was performed to measure the effect of MON1B on cell viability of colon cancer cells, which was inhibited time-dependently (12, 24, and 48 h) in the si-MON1B group, with significant differences at 24 and 48 h (P<0.05, Figure 2C). | |
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| Source | Sci Rep (2018;8:3891). Figure 4. CCK-8 (AbMole BioScience) | |
| Method | Cell viability assay | |
| Cell Lines | PLC5 cells | |
| Concentrations | 10 nmol/L | |
| Incubation Time | 48 h | |
| Results | In accordance with functional analysis, western blot confirmed that CCRK overexpression promoted cell proliferation by activating β-catenin/TCF signaling, which however significantly abrogated by bufalin | |
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| Source | Sci Rep (2018;8:3891). Figure 1. CCK-8 (AbMole BioScience) | |
| Method | Cell viability assay | |
| Cell Lines | PLC5 cells | |
| Concentrations | 10 nmol/L | |
| Incubation Time | 48 h | |
| Results | After 48 hours incubation, cell viability was measured by CCK-8 assay. In contrast with less influence on the growth of LO2 cells, bufalin exhibited strong ability to suppress the number of PLC5 cells in a dose-dependent manner. | |
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| Source | Cancer Biol Ther (2018 Jun 3;19(6):507-517). Figure 7. CCK-8 (Abmole Bioscience, Shanghai, China) | |
| Method | CCK-8 assay | |
| Cell Lines | C33A, Hcc94, HeLa, and SiHa cell lines | |
| Concentrations | ||
| Incubation Time | 72 h | |
| Results | As the results of the CCK-8 assay shown, the 72-hour treatment with buformin exhibited significant suppressive effects on cellular growth in C33A, Hcc94, and SiHa cells, but only exerted moderate effects in HeLa cells. | |
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| Source | Future Oncology (2018 Feb;14(3):241-253) . Figure 3. CCK-8 (AbMole BioScience, Shanghai, China) | |
| Method | Cell counting kit-8 assay | |
| Cell Lines | HeLa, SiHa, C33A and CasKi cells | |
| Concentrations | 10 μl | |
| Incubation Time | 2 h | |
| Results | Compared with its counterparts, knockdown of PXN suppressed cellular proliferation and induced cellular apoptosis | |
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| Source | PLoS One (2013). Figure 3. Cell counting kit-8 | |
| Method | Cell proliferation assay | |
| Cell Lines | Human colon cancer cell lines HT-29, LOVO, and Caco-2 | |
| Concentrations | 10 μL/well | |
| Incubation Time | 2 h | |
| Results | The effect of cPA on cell proliferation was determined using a colorimetric assay. We found that cPA inhibited the proliferation of HT-29 and LOVO cells but not of DLD-1 and Caco-2 cells, which have lower endogenous levels of PDE3B than HT-29 and LOVO cells. | |
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| Source | PLoS One (2013). Figure 4. Cell counting kit-8 | |
| Method | Cell viability | |
| Cell Lines | Human mesenchymal stem cells | |
| Concentrations | 20 µL/well | |
| Incubation Time | 3 h | |
| Results | In group A, the cell number remained stable during the first 3 days, followed by a continuous increase till day 14. In group B, the cell number was stable during the first 2 days, then started to increase, and attained a plateau on day 12. In group C (control group), the cell number (Fig. 4A) remained stable during the first 4 days in culture, then started to increase, and plateaued on day 8. | |
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Product Citations
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Mol Cancer. 2024 Jan;23(1):27.
Role of a novel circRNA-CGNL1 in regulating pancreatic cancer progression via NUDT4-HDAC4-RUNX2-GAMT-mediated apoptosis
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Nat Commun. 2024 Mar 9;15(1):2163.
Mi-2β promotes immune evasion in melanoma by activating EZH2 methylation
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Nat Commun. 2024 Mar 29;15(1):276.
Cell surface patching via CXCR4-targeted nanothreads for cancer metastasis inhibition
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Chem Eng J. 2024 Sep 18.
Leveraging chemotherapy-induced PD-L1 upregulation to potentiate targeted PD-L1 degradation using nanoparticle-based targeting chimeras
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J Control Release. 2024 Aug 09.
Biomimetic nanocomplex based corneal neovascularization theranostics
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Applied Materials Today. 2024 Jan;36.
A biomimetic three-dimensional porous scaffold of mineralized recombinant collagen-sodium alginate for efficiently repairing critical-size cranial defects
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Mater Today Bio. 2024 Aug;Volume 27, 101118.
Advanced topology of triply periodic minimal surface structure for osteogenic improvement within orthopedic metallic screw
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Front Med. 2024 Apr 22.
Targeting deubiquitinase OTUB1 protects vascular smooth muscle cells in atherosclerosis by modulating PDGFRβ
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Appl Mater Today. 2024 Oct 14.
Improved anti-malarial parasite efficacy with heparin-artemisinin nanoemulsions
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Phytomedicine. 2024 Sep 16.
Biochanin A suppresses Klf6-mediated Smad3 transcription to attenuate renal fibrosis in UUO mice
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Food Control. 2024 Feb.
Cellulose-based magnetic nanomaterials immobilized esterases as a reusable and effective detoxification agent for patulin in apple juice
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Pharmaceutics. 2024 Sep 03.
Self-Assembled Nanoparticles of Silicon (IV)–NO Donor Phthalocyanine Conjugate for Tumor Photodynamic Therapy in Red Light
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Chin Med J (Engl). 2024 Jan.
LONP1 ameliorates liver injury and improves gluconeogenesis dysfunction in acute-on-chronic liver failure
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J Mater Chem B. 2024 Sep 18.
Development and evaluation of 3D composite scaffolds with piezoelectricity and biofactor synergy for enhanced articular cartilage regeneration
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Mol Med. 2024 Aug 31;30(1):133.
AST-120 alleviates renal ischemia-reperfusion injury by inhibiting HK2-mediated glycolysis
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iScience. 2024 Jun 6.
Monoacylglycerol acyltransferase-2 inhibits colorectal carcinogenesis in APCmin+/- mice
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Cancer Sci. 2024 Apr 03.
YTHDC1-dependent m6A modification modulated FOXM1 promotes glycolysis and tumor progression through CENPA in triple-negative breast cancer
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Int Immunopharmacol. 2024 Feb 15;128:111323.
Downregulation of S100A11 promotes T cell infiltration by regulating cancer-associated fibroblasts in prostate cancer
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Marine Drugs. 2024 May.
Stem-Cell-Regenerative and Protective Effects of Squid (Symplectoteuthis oualaniensis) Skin Collagen Peptides against H2O2-Induced Fibroblast Injury
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Bioorg Chem. 2024 Feb;145:107187.
Chemical proteomics unveils that seventy flavors pearl pill ameliorates ischemic stroke by regulating oxidative phosphorylation
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Chem Biol Interact. 2024 Mar 8;110943.
The copper transporter, SLC31A1, transcriptionally activated by ELF3, imbalances copper homeostasis to exacerbate cisplatin-induced acute kidney injury through mitochondrial dysfunction
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Mol Pharm. 2024 Feb 26.
Sialic Acid Conjugate-Modified Cationic Liposomal Paclitaxel for Targeted Therapy of Lung Metastasis in Breast Cancer: What a Difference the Cation Content Makes
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Probiotics Antimicrob Proteins. 2024 May 11.
Temporin-GHaR Peptide Alleviates LPS-Induced Cognitive Impairment and Microglial Activation by Modulating Endoplasmic Reticulum Stress
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Cell Signal. 2024 Mar;117:111115.
LOC644656 promotes cisplatin resistance in cervical cancer by recruiting ZNF143 and activating the transcription of E6-AP
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Cell Signal. 2024 Apr 06;119:111165.
LncRNA HMOX1 alleviates renal ischemia-reperfusion-induced ferroptotic injury via the miR-3587/HMOX1 axis
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Int Immunopharmacol. 2024 Jun 29;51(1):428.
Evaluating tocilizumab safety and immunomodulatory effects under ocular HTLV-1 infection in vitro
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ACS Appl Bio Mater. 2024 May 24.
Hybrid Microneedle-Mediated Transdermal Delivery of Atorvastatin Calcium-Loaded Polymeric Micelles for Hyperlipidemia Therapy
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Mol Carcinog. 2024 Jan.
Knockout of Shcbp1 sensitizes immunotherapy by regulating α-SMA positive cancer-associated fibroblasts
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Sci Rep. 2024 Jan;14(1):1860.
Network pharmacology combined with experimental verification to explore the potential mechanism of naringenin in the treatment of cervical cancer
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Sci Rep. 2024 Feb 15;14(1):3783.
Exploring the therapeutic mechanisms and prognostic targets of Biochanin A in glioblastoma via integrated computational analysis and in vitro experiments
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Sci Rep. 2024 Apr 01;14(1):7624.
Aspirin/amoxicillin loaded chitosan microparticles and polydopamine modifed titanium implants to combat infections and promote osteogenesis
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Mol Carcinog. 2024 Apr 17.
Four and a half LIM domains 2 (FHL2) attenuates tumorigenesis of gastrointestinal stromal tumors (GISTs) by negatively regulating KIT signaling
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iScience. 2024 Aug 31.
Atractylodin modulates ASAH3L to improve galactose metabolism and inflammation to alleviate acute lung injury
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J Drug Target. 2024 May 7.
Celastrol nano-emulsions selectively regulate apoptosis of synovial macrophage for alleviating rheumatoid arthritis
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Reprod Biol Endocrinol. 2024 Apr 04;22(1):37.
Enhancing endometrial receptivity: the roles of human chorionic gonadotropin in autophagy and apoptosis regulation in endometrial stromal cells
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BMC Genomics. 2024 Apr 01;25(1):325.
MicroRNA-542-3p targets Pten to inhibit the myoblasts proliferation but suppresses myogenic differentiation independent of targeted Pten
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Poult Sci. 2024 May 23;103(8):103883.
Curcumin alleviates Aflatoxin B1-triggered chicken liver necroptosis by targeting the LOC769044/miR-1679/STAT1 axis
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Chemical Engineering Journal. 2024 Apr 09.
Novel nano-platinum induces autophagy through dual pathways in the treatment of osteosarcoma in cell lines with different P53 expression patterns
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J Sci Food Agric. 2024 Jan.
Effects of medicine food homologous materials on food allergy‐associated factors: intestinal oxidative stress, intestinal inflammation and Th2 immune response
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Heliyon. 2024 Mar 8.
Mitosis targeting in non-small lung cancer cells by inhibition of PAD4
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World J Stem Cells. 2024 Feb 26;16(2):207-227.
VX-509 attenuates the stemness characteristics of colorectal cancer stem-like cells by regulating the epithelial-mesenchymal transition through Nodal/Smad2/3 signaling
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Heliyon. 2024 Jan;10(2):e24415.
The construction, validation and promotion of the nomogram prognosis prediction model of UCEC, and the experimental verification of the expression and …
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Biomed Mater. 2024 Apr 11;19(3).
Bone morphogenetic protein-2 loaded triple helix recombinant collagen-based hydrogels for enhancing bone defect healing
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BMC Complement Med Ther. 2024 Jun 7;24(1):221.
Exploring the potential of Huangqin Tang in breast cancer treatment using network pharmacological analysis and experimental verification
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J Chromatogr A. 2024 Oct 11;1734:465322.
Target-specific affinity separation of the bioactive compounds from herbal extract using the spin column packed with the immobilized protein microspheres prior to LC-MS analysis
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Bioorg Med Chem. 2024 Feb;100:117635.
Cationic lipids from multi-component Passerini reaction for non-viral gene delivery: A structure-activity relationship study
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Gene. 2024 Jul 1;914:148406.
S100A6 mediated epithelial-mesenchymal transition affects chemosensitivity of colorectal cancer to oxaliplatin
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J Gene Med. 2024 May 1;26(5):e3685.
Autophagy-related CMTM6 promotes glioblastoma progression by activating Wnt/β-catenin pathway and acts as an onco-immunological biomarker
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J Pharm Biomed Anal. 2024 Apr 18.
Combined untargeted metabolomics and network pharmacology approaches to reveal the therapeutic role of withanolide B in psoriasis
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Urolithiasis. 2024 Mar 23;52(1):46.
N-acetylcysteine regulates oxalate induced injury of renal tubular epithelial cells through CDKN2B/TGF-β/SMAD axis
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Biochem Biophys Res Commun. 2024 May 8;718:150078.
High correlated color temperature artificial lighting impairs retinal pigment epithelium integrity and chloride ion transport: A potential mechanism for choroidal thinning
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Naunyn Schmiedebergs Arch Pharmacol. 2024 Aug 09.
Cinobufagin treatments suppress tumor growth by enhancing the expression of cuproptosis-related genes in liver cancer
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J Bioenerg Biomembr. 2024 Feb.
Silencing of METTL3 suppressed ferroptosis of myocardial cells by m6A modification of SLC7A11 in a YTHDF2 manner
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Funct Integr Genomics. 2024 Jan ;8;24(1):6.
Inhibition of FoxO1 alleviates polycystic ovarian syndrome by reducing inflammation and the immune response
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Mol Biol Rep. 2024 Mar 18;51(1):428.
GnT-V-mediated aberrant N-glycosylation of TIMP-1 promotes diabetic retinopathy progression
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Cardiovasc Diagn Ther. 2024 Aug 22.
The potential treatment of N-acetylcysteine as an antioxidant in the radiation-induced heart disease
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Mol Biotechnol. 2024 Mar 13;24.
HELLS Knockdown Inhibits the Malignant Progression of Lung Adenocarcinoma Via Blocking Akt/CREB Pathway by Downregulating KIF11
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Mol Biotechnol. 2024 May 16.
Involvement of circ_0029407 in Caerulein-Evoked Cytotoxicity in Human Pancreatic Cells via the miR-579-3p/TLR4/NF-κB Pathway
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Mater Adv. 2024 Jul 18.
MiRNA-20a-loaded graphene oxide–polyethylenimine enters bone marrow mesenchymal stem cells via clathrin-dependent endocytosis for efficient osteogenic differentiation
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Fitoterapia. 2024 Sep 24.
Sesquiterpenes from the seeds of Cichorium glandulosum and their anti- neuroinflammation activities
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Vet Microbiol. 2024 Sep;296:110175.
Alarming and calming: Dual functions of S100A9 on Mycoplasma gallisepticun infection in avian cells
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Discov Oncol. 2024 Apr 26;15(1):132.
AKR1B10 accelerates glycolysis through binding HK2 to promote the malignant progression of oral squamous cell carcinoma
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Food Science & Nutrition. 2024 Apr 17.
Penthorum chinense Pursh extract ameliorates hepatic steatosis by suppressing pyroptosis via the NLRP3/Caspase-1/GSDMD pathway
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Oncol Res. 2024 Jul 02;25(1):325.
IKIP downregulates THBS1/FAK signaling to suppress migration and invasion by glioblastoma cells
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Cell Mol Biol. 2024 Feb 29;70(2).
Declined circular RNA mitofusin 2 constrains the deterioration of Wilms tumor via modulating microRNA-372-3p/transforming growth factor-β receptor type 2 axis
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Ciência Rural, Santa Maria. 2024 Apr;e20230102.
Mechanism of astaxanthin relieving lipopolysaccharide (LPS)-induced acute liver injury in mice
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Chemical Engineering Journal. 2023 Jan 15;141122.
Near-ultraviolet and deep red dual-band mechanoluminescence for color manipulation and biomechanics detection
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Acta Neuropathol. 2023 Mar 16.
Mutations in ARHGEF15 cause autosomal dominant hereditary cerebral small vessel disease and osteoporotic fracture
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Int J Biol Sci. 2023 May 8;19(8):2458-2474.
YAP1 synergize with YY1 transcriptional co-repress DUSP1 to induce osimertinib resistant by activating the EGFR/MAPK pathway and abrogating autophagy in non-small cell lung cancer
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ACS Appl Mater Interfaces. 2023 Feb 24.
Injectable, Hierarchically Degraded Bioactive Scaffold for Bone Regeneration
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Front Immunol. 2023 May 1;14:1182851.
Inhibition of DAI refrains dendritic cells from maturation and prolongs murine islet and skin allograft survival
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Materials & Design. 2023 Nov 18.
Biomimetic collagen composite matrix-hydroxyapatite scaffold induce bone regeneration in critical size cranial defects
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Int J Biol Macromol. 2023 Jun 29;246:125608.
Electron beam irradiation degrades the toxicity and alters the protein structure of Staphylococcus aureus alpha-hemolysin
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Gastric Cancer. 2023 May 24.
SPRY4 inhibits and sensitizes the primary KIT mutants in gastrointestinal stromal tumors (GISTs) to imatinib
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Biomed Pharmacother. 2023 Sep;165:115252.
Cynarin alleviates intervertebral disc degeneration via protecting nucleus pulposus cells from ferroptosis
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Front Immunol. 2023 May 15;14:1171351.
Latroeggtoxin-VI protects nerve cells and prevents depression by inhibiting NF-κB signaling pathway activation and excessive inflammation
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Front Immunol. 2023 May 16;14:1159577.
Mannose-binding lectin suppresses macrophage proliferation through TGF-β1 signaling pathway in Nile tilapia
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Ecotoxicol Environ Saf. 2023 Mar 20;255:114796.
Exposure to nanoplastics induces mitochondrial impairment and cytomembrane destruction in Leydig cells
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Ecotoxicol Environ Saf. 2023 Dec 5;269:115784.
Patulin induces ROS-dependent cardiac cell toxicity by inducing DNA damage and activating endoplasmic reticulum stress apoptotic pathway
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J Mater Chem B. 2023 Sep 8.
A Novel Fluoropolymer as Protein Delivery Vector with Robust Adjuvant Effect for the Cancer Immunotherapy
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Arch Pharm Res. 2023 Oct 7.
Death-associated protein kinase 1 phosphorylates MDM2 and inhibits its protein stability and function
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Cell Oncol (Dordr). 2023 Jun 24.
LncRNA CCAT2 promotes malignant progression of metastatic gastric cancer through regulating CD44 alternative splicing
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Int J Mol Sci. 2023 Jan 5;24(2):1070.
Sulforaphane Suppresses H2O2-Induced Oxidative Stress and Apoptosis via the Activation of AMPK/NFE2L2 Signaling Pathway in Goat Mammary Epithelial Cells
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Int J Mol Sci. 2023 Feb 1;24(3):2799.
Uterine Flushing Fluid-Derived Let-7b Targets CXCL10 to Regulate Uterine Receptivity in Goats during Embryo Implantation
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Int. J. Mol. Sci. 2023 May 23;24(11), 9110.
The Role of Integrin Receptor’s α and β Subunits of Mouse Mesenchymal Stem Cells on the Interaction of Marine-Derived Blacktip Reef Shark (Carcharhinus melanopterus) Skin Collagen
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Can J Cardiol. 2023 Aug 2;S0828-282X(23)01573-8.
YAP facilitates NEDD4L-mediated ubiquitination and degradation of ACSL4 to alleviate ferroptosis in myocardial ischemia-reperfusion injury
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ACS Applied Nano Materials. 2023 Apr 3.
Multifaceted Pt Nanoclusters for Targeting Recognition, Cellular Uptake, and Therapy In Vivo and In Vitro in Chronic Myeloid Leukemia Cells
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J Anim Sci Biotechnol. 2023 May 3;14(1):61.
Sulforaphane prevents LPS-induced inflammation by regulating the Nrf2-mediated autophagy pathway in goat mammary epithelial cells and a mouse model of mastitis
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iScience. 2023 Jun 19;26(7):107158.
HDAC3 promotes macrophage pyroptosis via regulating histone deacetylation in acute lung injury
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Life Sci. 2023 Nov 10;335:122253.
Identification of the role of MCM6 in bladder cancer prognosis, immunotherapy response, and in vitro experimental investigation using multi-omics analysis
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Colloids and Surfaces B: Biointerfaces. 2023 Mar 17.
Development of Biodegradable Nanogels for Lipase Accelerated Drug Release of 5-Aminolevulinic Acid
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Aging (Albany NY). 2023 Sep 24;15(18):9661-9675.
Aberrant expression of AKR1B1 indicates poor prognosis and promotes gastric cancer progression by regulating the AKT-mTOR pathway
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Environ Sci Pollut Res Int. 2023 Mar;30(12):34188-34202.
Ginsenoside Rg1 regulates thiram-induced chondrocytes' apoptosis and angiogenesis in broiler chickens
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Mikrochim Acta. 2023 Nov 30;190(12):491.
Self-assembled miR-134-5p inhibitor nanoparticles ameliorate experimental bronchopulmonary dysplasia (BPD) via suppressing ferroptosis
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Bioorg Chem. 2023 Jan;130:106256.
Studies on crystal structures, optical, dyeing and biological properties of protoberberine alkaloids and their supramolecular salts
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J Ethnopharmacol. 2023 Jul 17;116925.
Sijunzi decoction ameliorates gastric precancerous lesions via regulating oxidative phosphorylation based on proteomics and metabolomics
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Cancers. 2023 Sep 13;15(18), 4539.
Prognostic Value of Necroptosis-Related Genes Signature in Oral Squamous Cell Carcinoma
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J Ethnopharmacol. 2023 Feb 10;302(Pt A):115885.
Gallic acid alleviates gastric precancerous lesions through inhibition of epithelial mesenchymal transition via Wnt/β-catenin signaling pathway
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Eur J Pharm Sci. 2023 Jan 6;182:106372.
Ultrasound-mediated mesoporous silica nanoparticles loaded with PDLIM5 siRNA inhibit gefitinib resistance in NSCLC cells by attenuating EMT
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Cell Cycle. 2023 Feb;22(3):276-290.
LncRNA HOXA10-AS promotes the progression of esophageal carcinoma by regulating the expression of HOXA10
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J Ethnopharmacol. 2023 Mar 6;116342.
Mass spectrometry-based metabolomics reveal Dendrobium huoshanense polysaccharide effects and potential mechanism of N-methyl-N'- nitro-N-nitrosoguanidine -induced damage in GES-1 cells
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Chem Biol Interact. 2023 Sep 9;384:110696.
Rosavin regulates bone homeostasis through HDAC1-induced epigenetic regulation of EEF2
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Chem Biol Interact. 2023 Oct 1;384:110723.
Metformin alleviates cerebral ischemia/reperfusion injury aggravated by hyperglycemia via regulating AMPK/ULK1/PINK1/Parkin pathway-mediated mitophagy and apoptosis
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J Drug Target. 2023 Feb 7;1-9.
Folate Receptor-Mediated Targeted Therapy for Rheumatoid Arthritis by Methotrexate-Phospholipid Complex Nano-emulsions
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Virus Res. 2023 Oct 15;336:199223.
Identification of γ-Fagarine as a novel antiviral agent against respiratory virus (hMPV) infection
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Toxins (Basel). 2023 Aug 31;15(9):537.
Establishment of SV40 Large T-Antigen-Immortalized Yak Rumen Fibroblast Cell Line and the Fibroblast Responses to Lipopolysaccharide
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Macromol Rapid Commun. 2023 Nov 28;e2300559.
Antibacterial and DNA‐Based Hydrogels in Situ Block TNF‐α to Promote Diabetic Alveolar Bone Rebuilding
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Arthritis Res Ther. 2023 Oct 26;25(1):212.
ACSL4 inhibition prevents macrophage ferroptosis and alleviates fibrosis in bleomycin-induced systemic sclerosis model
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Epigenetics. 2023 Dec;18(1):2175168.
Upregulation of KHDC1L promotes the proliferation and inhibits apoptosis in head and neck squamous cell carcinoma
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Mol Carcinog. 2023 May 22.
Overexpression of TYRO3 indicates poor prognosis and induces gastric cancer progression via AKT-mTOR pathway
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Mol Carcinog. 2023 Sep 22.
DDR1/2 enhance KIT activation and imatinib resistance of primary and secondary KIT mutants in gastrointestinal stromal tumors
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Microorganisms. 2023 Jul 21;11(7):1850.
A Recombinant Oncolytic Pseudorabies Virus Expressing Interleukin-18, Interferon-Gamma and PH20 Genes Promotes Systemic Antitumor Immunity
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Oral Dis. 2023 Mar;29(2):491-504.
microRNA‐17 is a tumor suppressor in oral squamous cell carcinoma and is repressed by LSD1
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Onco Targets Ther. 2023 Jun 20;16:425-440.
Esomeprazole Alleviates Cisplatin Resistance by Inhibiting the AKT/mTOR Pathway in Ovarian Cancer Cells
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Onco Targets Ther. 2023 Jun 20;16:425-440.
Esomeprazole Alleviates Cisplatin Resistance by Inhibiting the AKT/mTOR Pathway in Ovarian Cancer Cells
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HELIYON. 2023 Aug 10.
LncSUMO1P3 exacerbates malignant behaviors of esophageal squamous cell carcinoma cells via miR-486-5p/PHF8/CD151
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Purinergic Signal. 2023 Mar;19(1):145-153.
P2X7 receptor involved in antitumor activity of atractylenolide I in human cervical cancer cells
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NEUROCHEM J. 2023 Aug 30.
Xingnaojing Combined with Brain Glycoside Peptide Targets LncRNA-H19 and Regulates hsa-microRNA (miR)-138-5p/MAPK6 to Alleviate Acute Ischemic Stroke
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J Cancer. 2023 Aug 28;14(14):2670-2685.
Reduced FANCE Confers Genomic Instability and Malignant Behavior by Regulating Cell Cycle Progression in Endometrial Cancer
Cell Counting Kit-8 purchased from AbMole -
Acta Biochim Biophys Sin (Shanghai). 2023 Mar 25;55(3):472-483.
miR-424(322)-5p targets Ezh1 to inhibit the proliferation and differentiation of myoblasts
Cell Counting Kit-8 purchased from AbMole -
J Assist Reprod Genet. 2023 Dec 5.
The lncRNA LINC00339-encoded peptide promotes trophoblast adhesion to endometrial cells via MAPK and PI3K-Akt signaling pathways
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BMC Neurosci. 2023 Jan 27;24(1):8.
Circ VRK1/microRNA-17/PTEN axis modulates the angiogenesis of human brain microvascular endothelial cells to affect injury induced by oxygen-glucose
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Animals (Basel). 2023 Oct 31;13(21):3376.
Rhodotorula mucilaginosa ZTHY2 Attenuates Cyclophosphamide-Induced Immunosuppression in Mice
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Journal of Polymer Research. 2023 May 25;30:228.
Design of a bio-based flame retardant for polyvinyl alcohol with superior flame retardant, mechanical and UV-blocking properties
Cell Counting Kit-8 purchased from AbMole -
Animals (Basel). 2023 Dec;14(1):40.
Glucose Regulates Glucose Transport and Metabolism via mTOR Signaling Pathway in Bovine Placental Trophoblast Cells
Cell Counting Kit-8 purchased from AbMole -
Mol Biotechnol. 2023 Feb 20.
Hsa_circ_0137652 Regulates miR-1205/CCNB1 Axis to Accelerate the Malignancy of Breast Cancer
Cell Counting Kit-8 purchased from AbMole -
Gynecol Obstet Invest. 2023 Mar 7.
Expression of HMGB1-TLR4 in placentas from preeclamptic pregnancies and its effect on proliferation and invasion of HTR-8/SVneo cells
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Journal of Intensive Medicine. 2023 Oct 11;2023;20:0.
MicroRNA-30a inhibits cell proliferation in a sepsis-induced acute kidney injury model by targeting the YAP-TEAD complex
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Curr Drug Deliv. 2023 Aug 10.
A Novel Etanercept-loaded Nano-emulsion for Targeted Treatment of Inflammatory Arthritis via Draining Lymph Node
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Anticancer Drugs. 2023 Mar 1;34(3):439-450.
Exosomal miR-93-5p from cancer-associated fibroblasts confers malignant phenotypes on bladder cancer cells by targeting PAFAH1B1
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Open Med (Wars). 2023 Jul 3;18(1):20230698.
Dihydroartemisinin ameliorates cerebral I/R injury in rats via regulating VWF and autophagy-mediated SIRT1/FOXO1 pathway
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Korean J Physiol Pharmacol. 2023 Nov 1;27(6):521-531.
Three sesquiterpene lactones suppress lung adenocarcinoma by blocking TMEM16A-mediated Ca2+-activated Cl− channels
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Asian Pacific Journal of Tropical Biomedicine. 2023 Feb 24.
Salidroside attenuates oxygen and glucose deprivation-induced neuronal injury by inhibiting ferroptosis
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Natural Product Communications. 2023 Jan;18：1.
Phillyrin Inhibits Isoproterenol-Induced Cardiac Hypertrophy Via P38 and NF-κB Pathways
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Crit Rev Eukaryot Gene Expr. 2023;33(3):61-70..
Hsa_circ_0007334 Promotes the Osteogenic Differentiation and Proliferation of Human Bone Marrow Mesenchymal Stem Cells by Sponging miR-144-3p
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J Sichuan Univ (Med Sci). 2023 Jan 20;54(1):198−202.
Preparation and Tumor Targeting Analysis of Cell Membrane Nanovesicles Derived from Breast Cancer Cells
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Chin Pharm J. 2023 Apr.
Study on the Chemical Constituents of Roots from Euphorbia ebracteolata Hayata
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J Lab Med. 2023 Feb 2;47(1): 31–40.
The lncRNA prostate androgen-regulated transcript 1 (PART-1) promotes non-small cell lung cancer progression by regulating the miR-204-3p/IGFBP-2 pathway
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Chinese Journal of Immunology. 2023 Oct;2023,39(10).
Regulation and mechanism of Mannan-binding lectin on inflammatory and insulin resistance of 3T3-L1 adipocytes induced by lipopolysaccharide
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Tianjin Med J. 2023 Jun.
Influences of lncRNA SNHG11 on proliferation,apoptosis,migration and invasion of ovarian cancer cells by regulating miR-184/CARM1 signaling axis
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Nan Fang Yi Ke Da Xue Xue Bao. 2023 Apr 20;43(4): 507-515.
Yifei Jianpi recipe improves cigarette smoke-induced inflammatory injury and mucus hypersecretion in human bronchial epithelial cells by inhibiting the TLR4/NF-κB signaling pathway
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Nan Fang Yi Ke Da Xue Xue Bao. 2023 Apr 20;43(4): 507–515.
Yifei Jianpi recipe improves cigarette smoke-induced inflammatory injury and mucus hypersecretion in human bronchial epithelial cells by inhibiting the TLR4/NF-κB signaling pathway
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Reports of Biochemistry & Molecular Biology. 2023 Apr 1.
Farnesyltransferase (FTase) Inhibitors Increase Inhibition of KIT Mutants by Imatinib
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Chin Pharm J. 2023 Apr;58(8):668-674.
Study on the Chemical Constituents of Roots from Euphorbia ebracteolata Hayata
Cell Counting Kit-8 purchased from AbMole -
Small. 2022 Jul;18(27):e2201826.
Color‐Tunable Fluorescent Hierarchical Nanoassemblies with Concentration‐Encoded Emission
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research square. 2022 Aug.
Human umbilical cord mesenchymal stem cells conditioned medium exerts anti-tumor effects on KGN cells in a cell density-dependent manner through
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Research Square. 2022 Apr 21.
Nitidine chloride inhibits proliferation and induces apoptosis in colorectal cancer cells by activating the p53 signaling pathway
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Int J Biol Sci. 2022 Jan 31;18(4):1594-1611.
Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway
Cell Counting Kit-8 purchased from AbMole -
ACS Appl Mater Interfaces. 2022 Oct 19.
Novel Platinum Nanoclusters Activate PI3K/AKT/mTOR Signaling Pathway-Mediated Autophagy for Cisplatin-Resistant Ovarian Cancer Therapy
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Antiviral Res. 2022 Dec;208:105463.
HIV protease inhibitor attenuated astrocyte autophagy involvement in inflammation via p38 MAPK pathway
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Cell Death Dis. 2022 Mar 15;13(3):238.
Hepatic stellate cell mediates transcription of TNFSF14 in hepatocellular carcinoma cells via H2S/CSE-JNK/JunB signaling pathway
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Respir Res. 2022 Apr 12;23(1):93.
miR-489-3p promotes malignant progression of non-small cell lung cancer through the inactivation of Wnt/β-catenin signaling pathway via regulating USP48
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ACS Appl Polym Mater. 2022 Apr;497-508.
Biotin-Targeted Multifunctional Nanoparticles Encapsulating 10-Hydroxycamptothecin and Apoptin Plasmid for Synergistic Hepatocellular Carcinoma Treatment
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Biomed Pharmacother. 2022 Feb 26;148:112665.
PI3K inhibitor 3-MA promotes the antiproliferative activity of esomeprazole in gastric cancer cells by downregulating EGFR via the PI3K/FOXO3a pathway
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Oxid Med Cell Longev. 2022 Apr 16;2022:4505513.
Nrf2-Mediated Ferroptosis Inhibition Exerts a Protective Effect on Acute-on-Chronic Liver Failure
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Oxid Med Cell Longev. 2022 Mar 25;2022:8128028.
Establishment of Immortalized Yak Ruminal Epithelial Cell Lines by Lentivirus-Mediated SV40T and hTERT Gene Transduction
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Biomacromolecules. 2022 Nov 8.
Sodium Alginate-Doping Cationic Nanoparticle As Dual Gene Delivery System for Genetically Bimodal Therapy
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Bioengineered. 2022 Mar;13(3):7303-7315.
Circular RNA HECTD1 knockdown inhibits transforming growth factor-beta/ small mothers against decapentaplegic (TGF-β/Smad) signaling to reduce hypertrophic scar fibrosis
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Bioengineered. 2022 Mar;13(3):4898-4910.
Germacrone alleviates okadaic acid-induced neurotoxicity in PC12 cells via M1 muscarinic receptor-mediated Galphaq (Gq)/phospholipase C beta (PLCβ)/ protein kinase C (PKC) signaling
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Mol Cancer Res. 2022 Apr 1;20(4):515-526.
Transcription Factor FOSL1 Enhances Drug Resistance of Breast Cancer through DUSP7-Mediated Dephosphorylation of PEA15
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Int J Mol Sci. 2022 Aug 8;23(15):8798.
PEBP4 Directs the Malignant Behavior of Hepatocellular Carcinoma Cells via Regulating mTORC1 and mTORC2
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Med J Chin PLA. 2022 Jun 28;47-6.
Effect of NCAPH knockout on proliferation and invasion of pancreatic cancer cells
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Food Chem Toxicol. 2022 Feb;160:112805.
Bisphenol S exposure induces cytotoxicity in mouse Leydig cells
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Front Cell Infect Microbiol. 2022 Jun 27;12:907813.
Chimonanthus nitens Oliv. Leaf Granule Ameliorates DSS-Induced Acute Colitis Through Treg Cell Improvement, Oxidative Stress Reduction, and Gut
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Colloids Surf B Biointerfaces. 2022 Apr;212:112372.
One-step surface modification strategy with composition-tunable microgels: From bactericidal surface to cell-friendly surface
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Front Pharmacol. 2022 Jul 19;13:933096.
Proteomics and Metabolomics Unveil Codonopsis pilosula (Franch.) Nannf. Ameliorates Gastric Precancerous Lesions via Regulating Energy Metabolism
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Front Pharmacol. 2022 Mar 7;13:817596.
Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKα/β-NF-Κb and Keap1-Nrf2 Signalling Pathways
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J Agric Food Chem. 2022 Jan 26;70(3):857-868.
Fabrication of Epsilon-Polylysine-Based Magnetic Nanoflowers with Effective Antibacterial Activity against Alicyclobacillus acidoterrestris
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FASEB J. 2022 Nov;36(11):e22580.
Transforming growth factor-β receptor type 2 is required for heparin-binding protein-induced acute lung injury and vascular leakage for transforming growth factor-β/Smad/Rho signaling pathway activation
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Front Oncol. 2022 Jun 3;12:898917.
Biomarking and induction of apoptosis in ovarian cancer using bifunctional polyethyleneimine-caged platinum nanoclusters
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Foods. 2022 Mar 4;11(5):749.
Effects of Selenium Nanoparticles on Preventing Patulin-Induced Liver, Kidney and Gastrointestinal Damage
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Front Chem. 2022 Jul 22;10:958561.
MicroRNA-29b/graphene oxide-polyethyleneglycol-polyethylenimine complex incorporated within chitosan hydrogel promotes osteogenesis
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Front Chem. 2022 Sep 21;10:951434.
A mitochondria-targeted nano-platform for pancreatic cancer therapy
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J Ethnopharmacol. 2022 October 5;296:115519.
Lycium barbarum L. and Salvia miltiorrhiza Bunge protect retinal pigment epithelial cells through endoplasmic reticulum stress
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Biology (Basel). 2022 Jul 26;11(8):1115.
The Tropomyosin Family as Novel Biomarkers in Relation to Poor Prognosis in Glioma
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Biology (Basel). 2022 Jul 26;11(8):1115.
The Tropomyosin Family as Novel Biomarkers in Relation to Poor Prognosis in Glioma. Biology 2022, 11, 1115
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Sci Rep. 2022 Feb 24;12(1):3122.
RFC2: a prognosis biomarker correlated with the immune signature in diffuse lower-grade gliomas
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Molecules. 2022 May 6;27(9):2994.
Inosine and D-Mannose Secreted by Drug-Resistant Klebsiella pneumoniae Affect Viability of Lung Epithelial Cells
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Cell Signal. 2022 Oct;98:110429.
Notch4 affects the proliferation and differentiation of deer antler chondrocytes through the Smad3/lncRNA27785
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BMC Cancer. 2022 Nov 17;22(1):1184.
CX3CL1 promotes cell sensitivity to ferroptosis and is associated with the tumor microenvironment in clear cell renal cell carcinoma
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J Immunol Res. 2022 Jul 27;2022:4201283.
A Novel Identified Long Intergenic Noncoding RNA, LINC01574, Contributes to Breast Cancer Deterioration via the Regulation of miR-6745/TTYH3 Axis
Cell Counting Kit-8 purchased from AbMole -
J Oncol. 2022 May 7;2022:7981711.
PITPNA-AS1/miR-98-5p to Mediate the Cisplatin Resistance of Gastric Cancer
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J Oncol. 2022 Apr 28;2022:3433406.
SNHG3 Affects Gastric Cancer Development by Regulating SEPT9 Methylation
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J Bone Oncol. 2022 Jan 19;33:100412.
MiR-451a promotes cell growth, migration and EMT in osteosarcoma by regulating YTHDC1-mediated m6A methylation to activate the AKT/mTOR signaling pathway
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J Cancer(2022). 2022 Jan 1;13(1):343-353.
Long non-coding RNA MAGI2-AS3 inactivates STAT3 pathway to inhibit prostate cancer cell proliferation via acting as a microRNA-424-5p sponge
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Toxicol Appl Pharmacol. 2022 Sep 8;116232.
The inhibition of centromere protein K causes anticancer effects in breast carcinoma via effects on the FAK/PI3K/AKT/mTOR pathway
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J Tissue Eng Regen Med. 2022 Aug 18.
The effect of resolvin D1 on bone regeneration in a rat calvarial defect model
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Environ Toxicol. 2022 Mar;37(3):527-538.
Inhibition of Ras protein activator like 2 produces antitumor effects in gastric cancer via the suppression of YAP1 activation
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Exp Cell Res. 2022 Oct 15;421(2):113388.
FANCD2 promotes the malignant behavior of endometrial cancer cells and its prognostic value
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J Sci Food Agric. 2022 Nov 8.
Comparison of interaction, structure and cell proliferation of α‐Lactalbumin‐safflower yellow complex induced by microwave heating and conventional heating
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Chinese Journal of Tissue Engineering Research. 2022 July;2095-4344(2023)10-01547-06.
Effects of chiral polyethyleneimine/graphene oxide/phenylalanine interface on adhesion and proliferation of multilineage-differentiating stress enduring cells
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Purinergic Signal. 2022 Mar 2.
P2X7 receptor involved in antitumor activity of atractylenolide I in human cervical cancer cells
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Neurotox Res. 2022 Jun;40(3):825-836.
Hsa_circ_0008344 Promotes Glioma Tumor Progression and Angiogenesis Presumably by Regulating miR-638/SZRD1 Pathway
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J Healthc Eng. 2022 Jan 6;2022:2373580.
circRNA LDLRAD3 Enhances the Malignant Behaviors of NSCLC Cells via the miR-20a-5p-SLC7A5 Axis Activating the mTORC1 Signaling Pathway
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Prostaglandins Other Lipid Mediat. 2022 Aug 5;163:106667.
FBXO31 suppresses lipogenesis and tumor progression in glioma by promoting ubiquitination and degradation of CD147
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Vet Res. 2022 Jul 19;53(1):58.
S1PR1 regulates NDV-induced IL-1β expression via NLRP3/caspase-1 inflammasome
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Chin J Nat Med. 2022 Apr;20(4):282-289.
Study on the mechanism of Wuzi-Yanzong-Wan-medicated serum interfering with the mitochondrial permeability transition pore in the GC-2 cell induced by atractyloside
Cell Counting Kit-8 purchased from AbMole -
Biochem Cell Biol. 2022 Apr 7.
Decursin ameliorates carbon tetrachloride-induced liver fibrosis by facilitating ferroptosis of hepatic stellate cells
Cell Counting Kit-8 purchased from AbMole -
Cell Biol Int. 2022 Jan;46(1):106-117.
Exosome-mediated lncRNA SNHG11 regulates angiogenesis in pancreatic carcinoma through miR-324-3p/VEGFA axis
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Cancer Biother Radiopharm. 2022 Aug;37(6):451-465.
Long noncoding RNA small nucleolar RNA host Gene 3 mediates prostate cancer migration, invasion, and epithelial-mesenchymal transition by sponging miR-487a
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Ann Transl Med. 2022 Apr;10(8):432.
Melatonin exerts anti-angiogenic and anti-inflammatory effects in alkali-burned corneas
Cell Counting Kit-8 purchased from AbMole -
Electrophoresis. 2022 Jul;43(13-14):1466-1475.
Microfluidic platform for studying the anti‐cancer effect of ursolic acid on tumor spheroid
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Reprod Toxicol. 2022 Jan 3;S0890-6238(21)00193-3.
MicroRNA-20a-5p Inhibits the Autophagy and Cisplatin Resistance in Ovarian Cancer via Regulating DNMT3B-mediated DNA Methylation of RBP1
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Dis Markers. 2022 Aug 16;2022:6329097.
circCNN2 Accelerates Cell Proliferation and Invasion in Lung Squamous Cell Carcinoma via Regulating miR-184/E2F1 and Activating MAPK Signaling Pathway
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Pathol Res Pract. 2022 Jul;235:153882.
Exosomal MiR-423–3p inhibits macrophage M2 polarization to suppress the malignant progression of cervical cancer
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Pathol Res Pract. 2022 Jun;234:153855.
MicroRNA-377-3p promotes cell proliferation and inhibits cell cycle arrest and cell apoptosis in hepatocellular carcinoma by affecting EGR1-mediated p53 activation
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RADIATION RESEARCH. 2022 Oct 21.
MG149 Inhibits MOF-Mediated p53 Acetylation to Attenuate X-Ray Radiation-Induced Apoptosis in H9c2 Cells
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Hum Exp Toxicol. 2022 Jan-Dec;41:9603271221097363.
Icariin inhibits gastric cancer cell growth by regulating the hsa_circ_0003159/miR-223-3p/NLRP3 signaling axis
Cell Counting Kit-8 purchased from AbMole -
Appl Biochem Biotechnol Appl Biochem Biotechnol. 2022 Jul 1.
Apatinib Through Activating the RhoA/ROCK Signaling Pathway to Cause Dysfunction of Vascular Smooth Muscle CellsMuscle Cells
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e-Polymers. 2022 May 30.
Multifunctional nanoparticles for targeted delivery of apoptin plasmid in cancer treatment
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J Appl Polym Sci. 2022 Dec 2.
Synthesis of water‐soluble protoporphyrin IX polymers and their photodynamic application
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J Mol Neurosci. 2022 Jun;72(6):1195-1207.
CircRFX3 Up-regulates Its Host Gene RFX3 to Facilitate Tumorigenesis and Progression of Glioma
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In Vitro Cell Dev Biol Anim. 2022 Mar;58(3):220-231.
Effects of 4-vinylcyclohexene diepoxide on the cell cycle, apoptosis, and steroid hormone secretion of goat ovarian granulosa cells
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Mol Biol Rep. 2022 Oct 6;Online ahead of print..
Dual effect of ultraviolet B on cholesterol efflux and regulated by ultraviolet radiation resistance-associated gene-mediated autophagy
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Evid Based Complement Alternat Med. 2022 May 11;2022:6446150.
Circ_0001998 Regulates the Proliferation, Invasion, and Apoptosis of Lung Adenocarcinoma via Sponging miR-145
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Evid Based Complement Alternat Med. 2022 Jul 15;2022:1955101.
Icariin Regulates the hsa_circ_0003159/eIF4A3/bcl-2 Axis to Promote Gastric Cancer Cell Apoptosis
Cell Counting Kit-8 purchased from AbMole -
Food Science and Technology. 2022 Dec 4.
Non-enzymatic browning of lotus root during boiling
Cell Counting Kit-8 purchased from AbMole -
J Cell Mol Med. 2022 May;26(10):2819-2830.
Calpain‐1 mediates vascular remodelling and fibrosis via HIF‐1α in hypoxia‐induced pulmonary hypertension
Cell Counting Kit-8 purchased from AbMole -
Bladder Cancer. 2022 May.
SH3BP5-AS1/IGF2BP2/VDAC2 Axis Promotes the Apoptosis and Ferroptosis of Bladder Cancer Cells
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Cellualr and Molecular Biology. 2022 Apr 30;68(4):75-85.
LINC01140 Regulates Radiosensitivity of Nasopharyngeal Carcinoma Cells Through the ceRNA Network
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Nan Fang Yi Ke Da Xue Xue Bao. 2022 May 20;42(5):673-680.
Hyperoside protects mouse spermatocytes GC-2 cells from oxidative damage by activating the Keap1/Nrf2/HO-1 pathway
Cell Counting Kit-8 purchased from AbMole -
Nucleic Acids Res. 2021 Mar 18;49(5):2848-2858.
HuB and HuD repress telomerase activity by dissociating HuR from TERC
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Exp Ther Med. 2021 Sep;22(3):980.
Sorafenib prevents the proliferation and induces the apoptosis of liver cancer cells by regulating autophagy and hypoxia-inducible factor-1
Cell Counting Kit-8 purchased from AbMole -
Food Hydrocolloids. 2021 Dec;Volume 121, 107036.
Microwave irradiation treatment improved the structure, emulsifying properties and cell proliferation of laccase-crosslinked α-lactalbumin
Cell Counting Kit-8 purchased from AbMole -
J Hazard Mater. 2021 Aug 15;416:126138.
New insights into crosstalk between pyroptosis and autophagy co-induced by molybdenum and cadmium in duck renal tubular epithelial cells
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Cell Death Dis. 2021 Mar 22;12(4):302.
Kinesin family member 18B regulates the proliferation and invasion of human prostate cancer cells
Cell Counting Kit-8 purchased from AbMole -
Oncogene. 2021 Mar;40(9):1706-1720.
The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2 USP11 deubiquitinates and stabilizes NRF2
Cell Counting Kit-8 purchased from AbMole -
Biomed Pharmacother. 2021 Dec;144:112360.
The endocytic pathway of Pt nanoclusters and their induced apoptosis of A549 and A549/Cis cells through c-Myc/p53 and Bcl-2/caspase-3 signaling pathways
Cell Counting Kit-8 purchased from AbMole -
Ecotoxicol Environ Saf. 2021 Nov 12;228:112981.
Taurine is an effective therapy against thiram induced tibial dyschondroplasia via HIF-1α/VEGFA and β-catenin/GSK-3β pathways in broilers
Cell Counting Kit-8 purchased from AbMole -
Ecotoxicol Environ Saf. 2021 Nov 12;228:112981.
Taurine is an effective therapy against thiram induced tibial dyschondroplasia via HIF-1α/VEGFA and β-catenin/ GSK-3β pathways in broilers
Cell Counting Kit-8 purchased from AbMole -
Arab J Chem. 2021 Nov;14(11):103399.
Bisphenol A and bisphenol AF co-exposure induces apoptosis in human granulosa cell line KGN through intracellular stress-dependent mechanisms
Cell Counting Kit-8 purchased from AbMole -
Int J Mol Sci. 2021 Sep 9;22(18):9759.
Ablation of KDM2A Inhibits Preadipocyte Proliferation and Promotes Adipogenic Differentiation
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Front Pharmacol. 2021 Oct 26;12:753676.
Discovery of a series of theophylline derivatives containing1, 2, 3-triazole for treatment of non-small cell lung cancer (NSCLC)
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Helicobacter. 2021 Jun;26(3):e12807.
Oral multivalent epitope vaccine, based on UreB, HpaA, CAT, and LTB, for prevention and treatment of Helicobacter pylori infection in C57BL / 6 mice
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Cancer Cell Int. 2021 Sep 10;21(1):481.
Knockdown of PGM1 enhances anticancer effects of orlistat in gastric cancer under glucose deprivation
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Aging (Albany NY). 2021 Jul 28;13(14):18223-18237.
Combination of rapamycin and SAHA enhanced radiosensitization by inducing autophagy and acetylation in NSCLC
Cell Counting Kit-8 purchased from AbMole -
J Cell Mol Med. 2021 Jul;25(14):6963-6975.
Fractalkine aggravates LPS-induced macrophage activation and acute kidney injury via Wnt/β-catenin signalling pathway
Cell Counting Kit-8 purchased from AbMole -
J Cell Mol Med. 2021 Jul;25(14):6963-6975.
Fractalkine aggravates LPS-induced macrophage activation and acute kidney injury via Wnt/β-catenin signalling pathway
Cell Counting Kit-8 purchased from AbMole -
J Agric Food Chem. 2021 Aug 25;69(33):9529-9535.
Identity, Synthesis, and Cytotoxicity of Forchlorfenuron Metabolites in Kiwifruit
Cell Counting Kit-8 purchased from AbMole -
Sci Rep. 2021 Mar.
PITPNA-AS1 Activated by H3K27ac Sponged miR-98-5p to Regulate Cisplatin Resistance in Gastric Cancer
Cell Counting Kit-8 purchased from AbMole -
Mol Pharm. 2021 Dec 6;18(12):4543-4552.
MR/NIRF Dual-Mode Imaging of αvβ3 Integrin-Overexpressing Tumors Using a Lipopeptide-Based Contrast Agent
Cell Counting Kit-8 purchased from AbMole -
Front Oncol. 2021 Jan 29;10:614067.
Solasonine Suppresses the Proliferation of Acute Monocytic Leukemia Through the Activation of the AMPK/FOXO3A Axis
Cell Counting Kit-8 purchased from AbMole -
ACS Biomater Sci Eng. 2021 Apr 12;7(4):1394-1402.
One-Pot Synthesis-Biocompatible Copper-Tripeptide Complex as a Nanocatalytic Medicine to Enhance Chemodynamic Therapy
Cell Counting Kit-8 purchased from AbMole -
J Clin Transl Hepatol. 2021 Nov 19.
Oncolytic Activity of Wild-type Newcastle Disease Virus HK84 Against Hepatocellular Carcinoma Associated with Activation of Type I Interferon Signaling
Cell Counting Kit-8 purchased from AbMole -
J Food Compost Anal. 2021 Jun;Volume 102, 104067.
Supercritical CO2 extraction, structural analysis and bioactivity of polysaccharide from Grifola frondosa
Cell Counting Kit-8 purchased from AbMole -
Cell Cycle. 2021 May;20(9):819-828.
NRF1-regulated CircNSUN2 promotes lymphoma progression through activating Wnt signaling pathway via stabilizing HMGA1
Cell Counting Kit-8 purchased from AbMole -
Cell Signal. 2021 Oct;86:110084.
Deficiency of tenascin-C attenuated cardiac injury by inactivating TLR4/NLRP3/caspase-1 pathway after myocardial infarction
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Lipids Health Dis. 2021 Nov 25;20(1):167.
Accumulation of LDL/ox-LDL in the necrotic region participates in osteonecrosis of the femoral head: a pathological and in vitro study
Cell Counting Kit-8 purchased from AbMole -
Environ Toxicol. 2021 Dec;36(12):2500-2511.
Angiomotin-like 1 plays a tumor-promoting role in glioma by enhancing the activation of YAP1 signaling
Cell Counting Kit-8 purchased from AbMole -
Int J Mol Med. 2021 May;47(5):70.
circNRIP1 facilitates keloid progression via FXR1‑mediated upregulation of miR‑503‑3p and miR‑503‑5p
Cell Counting Kit-8 purchased from AbMole -
Lipids Health Dis. 2021 Apr 26;20(1):40.
Elucidation of SIRT-1/PGC-1α-associated mitochondrial dysfunction and autophagy in nonalcoholic fatty liver disease
Cell Counting Kit-8 purchased from AbMole -
Life Sci. 2021 Jan 15;265:118853.
Circadian clock gene BMAL1 reduces urinary calcium oxalate stones formation by regulating NRF2/HO-1 pathway
Cell Counting Kit-8 purchased from AbMole -
DNA Cell Biol. 2021 Jul;40(7):895-905.
AEG-1 Knockdown Sensitizes Glioma Cells to Radiation Through Impairing Homologous Recombination Via Targeting RFC5
Cell Counting Kit-8 purchased from AbMole -
Bioengineered. 2021 Dec;12(1):2499-2510.
Targeting the miR-6734-3p/ZEB2 axis hampers development of non-small cell lung cancer (NSCLC) and increases susceptibility of cancer cells to cisplatin treatment
Cell Counting Kit-8 purchased from AbMole -
BMC Cancer. 2021 Feb 25;21(1):195.
Blockage of AMPK-ULK1 pathway mediated autophagy promotes cell apoptosis to increase doxorubicin sensitivity in breast cancer (BC) cells: an in vitro study
Cell Counting Kit-8 purchased from AbMole -
DNA Cell Biol. 2021 Oct;40(10):1308-1316.
MUC1 Promotes Mesangial Cell Proliferation and Kidney Fibrosis in Diabetic Nephropathy Through Activating STAT and β-Catenin Signal Pathway
Cell Counting Kit-8 purchased from AbMole -
Reprod Sci. 2021 Jun 2.
LncRNA HOXA-AS2 Activates the Notch Pathway to Promote Cervical Cancer Cell Proliferation and Migration
Cell Counting Kit-8 purchased from AbMole -
ChemistryOpen. 2021 Sep;10(9):882-888.
Distinguishable Targeting of Non‐Small Cell Lung Cancer Using Hyaluronan Functionalized Platinum Nanoclusters and Their Inhibition Behaviors of Proliferation, Invasion, Migration
Cell Counting Kit-8 purchased from AbMole -
FEBS Open Bio. 2021 Jun 8;11(8):2186-2197.
Silencing of cystatin SN abrogates cancer progression and stem cell properties in papillary thyroid carcinoma
Cell Counting Kit-8 purchased from AbMole -
Pathol Int. 2021 Nov;71(11):741-751.
ASMTL‐AS1 impedes the malignant progression of lung adenocarcinoma by regulating SAT1 to promote ferroptosis
Cell Counting Kit-8 purchased from AbMole -
Biomed Res Int. 2021 Mar 23;2021:5542545.
Sirt-1 Regulates Physiological Process and Exerts Protective Effects against Oxidative Stress
Cell Counting Kit-8 purchased from AbMole -
Folia Histochem Cytobiol. 2021;59(4):271-281.
LINC00839/miR-519d-3p/JMJD6 axis modulated cell viability, apoptosis, migration and invasiveness of lung cancer cells
Cell Counting Kit-8 purchased from AbMole -
Pak Vet J. 2021 Mar.
Evaluation of the PBMC Proliferation, Apoptosis and Cytokines Profiling in Cattle Infected with Mycoplasma bovis Strain 07801
Cell Counting Kit-8 purchased from AbMole -
Research Square. 2021 Jul.
miR-3587 Targets HMOX1 to Attenuate Ferroptotic Renal Injury Following Ischemia-Reperfusion
Cell Counting Kit-8 purchased from AbMole -
Sci Adv. 2020 Jul 10;6(28):eaba7260.
A basal-bolus insulin regimen integrated microneedle patch for intraday postprandial glucose control
Cell Counting Kit-8 purchased from AbMole -
Cell Death Dis. 2020 Aug 20;11(8):664.
Long noncoding RNA TTN-AS1 facilitates tumorigenesis and metastasis by maintaining TTN expression in skin cutaneous melanoma
Cell Counting Kit-8 purchased from AbMole -
ACS Appl Mater Interfaces. 2020 Apr 29;12(17):19268-19276.
Universal Antibacterial Surfaces Fabricated From Quaternary Ammonium Salt-Based PNIPAM Microgels.
Cell Counting Kit-8 purchased from AbMole -
J Hazard Mater. 2020 Apr 15;388:121802.
Thiol-functionalized inactivated yeast embedded in agar aerogel for highly efficient adsorption of patulin in apple juice.
Cell Counting Kit-8 purchased from AbMole -
Biomed Pharmacother. 2020 May;125:109924.
MiR-130a Alleviated High-Glucose Induced Retinal Pigment Epithelium (RPE) Death by Modulating TNF-α/SOD1/ROS Cascade Mediated Pyroptosis.
Cell Counting Kit-8 purchased from AbMole -
Biomed Pharmacother. 2020 May 25;128:110244.
Emodin Succinyl Ester Inhibits Malignant Proliferation and Migration of Hepatocellular Carcinoma by Suppressing the Interaction of AR and EZH2
Cell Counting Kit-8 purchased from AbMole -
Carbohydr Polym. 2020 Jan 1;227:115314.
Structural characterisation and immunomodulatory activity of polysaccharides from white asparagus skin.
Cell Counting Kit-8 purchased from AbMole -
J Exp Clin Cancer Res. 2020 May 24;39(1):93.
TFEB-NF-κB Inflammatory Signaling Axis: A Novel Therapeutic Pathway of Dihydrotanshinone I in Doxorubicin-Induced Cardiotoxicity
Cell Counting Kit-8 purchased from AbMole -
Chemosphere. 2020 Aug;253:126707.
Bisphenol A and Its Analogues Bisphenol S, Bisphenol F and Bisphenol AF Induce Oxidative Stress and Biomacromolecular Damage in Human Granulosa KGN Cells.
Cell Counting Kit-8 purchased from AbMole -
Aging (Albany NY). 2020 Jun 9;12(11):11025-11041.
LncRNA ADAMTS9-AS2 inhibits gastric cancer (GC) development and sensitizes chemoresistant GC cells to cisplatin by regulating miR-223-3p/NLRP3 axis
Cell Counting Kit-8 purchased from AbMole -
Aging (Albany NY). 2020 May 4;12(9):8137-8150.
Overexpression of METTL3 attenuates high-glucose induced RPE cell pyroptosis by regulating miR-25-3p/PTEN/Akt signaling cascade through DGCR8
Cell Counting Kit-8 purchased from AbMole -
Aging (Albany NY). 2020 Jun 9;12(11):11025-11041.
LncRNA ADAMTS9-AS2 inhibits gastric cancer (GC) development and sensitizes chemoresistant GC cells to cisplatin by regulating miR-223-3p/NLRP3 axis
Cell Counting Kit-8 purchased from AbMole -
J Cell Mol Med. 2020 Mar;24(5):2901-2916.
Verbascoside Inhibits Progression of Glioblastoma Cells by Promoting Let-7g-5p and Down-Regulating HMGA2 via Wnt/beta-catenin Signalling Blockade
Cell Counting Kit-8 purchased from AbMole -
Cell Cycle. 2020 Aug;19(15):1857-1868.
Hsa_circ_0009910: oncogenic circular RNA targets microRNA-145 in ovarian cancer cells
Cell Counting Kit-8 purchased from AbMole -
World J Gastroenterol. 2020 Jun 7;26(21):2810-2820.
Gan Shen Fu Fang ameliorates liver fibrosis in vitro and in vivo by inhibiting the inflammatory response and extracellular signal-regulated kinase phosphorylation
Cell Counting Kit-8 purchased from AbMole -
Life Sci. 2020 Oct 15;259:118180.
Upregulation of miR-133a-3p enhances Bufothionine-induced gastric cancer cell death by modulating IGF1R/PI3K/Akt signal pathway mediated ER stress
Cell Counting Kit-8 purchased from AbMole -
Biofactors. 2020 Jan 8.
Propofol exerts neuroprotective functions by down-regulating microRNA-19a in glutamic acid-induced PC12 cells.
Cell Counting Kit-8 purchased from AbMole -
Onco Targets Ther. 2020 Sep 28;13:9543-9558.
Targeted Inhibition of P4HB Promotes Cell Sensitivity to Gemcitabine in Urothelial Carcinoma of the Bladder
Cell Counting Kit-8 purchased from AbMole -
Cell Cycle. 2020 May;19(10):1067-1076.
Hypoxia-induced Apoptosis of Cardiomyocytes Is Restricted by Ginkgolide B-downregulated microRNA-29.
Cell Counting Kit-8 purchased from AbMole -
IUBMB Life. 2020 Jun 27.
Effects of genetic variations in Acads gene on the risk of chronic obstructive pulmonary disease
Cell Counting Kit-8 purchased from AbMole -
Eur J Pharmacol. 2020 May 26;173212.
Pinocembrin Alleviates Glucocorticoid-Induced Apoptosis by Activating Autophagy via Suppressing the PI3K/Akt/mTOR Pathway in Osteocytes
Cell Counting Kit-8 purchased from AbMole -
Exp Biol Med (Maywood). 2020 Jun;245(11):925-932.
Circular RNA circ-CDYL sponges miR-1180 to elevate yes-associated protein in multiple myeloma
Cell Counting Kit-8 purchased from AbMole -
Vet Res. 2020 Apr 10;51(1):53.
Newcastle Disease Virus RNA-induced IL-1β Expression via the NLRP3/caspase-1 Inflammasome
Cell Counting Kit-8 purchased from AbMole -
J Appl Microbiol. 2020 Sep 29.
Enhanced in vitro antimicrobial activity of amphotericin B with berberine against dual-species biofilms of Candida albicans and Staphylococcus aureus
Cell Counting Kit-8 purchased from AbMole -
Onco Targets Ther. 2020 May 4;13:3729-3737.
Circular RNA circTUBGCP3 Is Up-Regulated and Promotes Cell Proliferation, Migration and Survivability via Sponge mir-30b in Osteosarcoma.
Cell Counting Kit-8 purchased from AbMole -
Biochem Biophys Res Commun. 2020 Sep 10;530(1):47-53.
LncRNA Linc-PINT inhibits miR-523-3p to hamper retinoblastoma progression by upregulating Dickkopf-1 (DKK1)
Cell Counting Kit-8 purchased from AbMole -
Exp Physiol. 2020 Sep 22.
Involvement of the lncRNA AFAP1-AS1/microRNA-195/E2F3 axis in proliferation and migration of enteric neural crest stem cells of Hirschsprung's disease
Cell Counting Kit-8 purchased from AbMole -
FEBS Open Bio. 2020 Dec 19.
Nicotinamide mononucleotide (NMN) protects bEnd.3 cells against H 2 O 2 -induced damage via NAMPT and the NF-κB p65 signalling pathway
Cell Counting Kit-8 purchased from AbMole -
Naunyn Schmiedebergs Arch Pharmacol. 2020 Feb 8.
Knock-down of LncRNA-XIST Induced Glioma Cell Death and Inhibited Tumorigenesis by Regulating miR-137/SLC1A5 Axis-Mediated ROS Production
Cell Counting Kit-8 purchased from AbMole -
Colcom. 2020 Jul;Volume 37, 100268.
Antibacterial coatings based on microgels containing quaternary ammonium ions: Modification with polymeric sugars for improved cytocompatibility
Cell Counting Kit-8 purchased from AbMole -
J Clin Lab Anal. 2020 Feb 28;e23249.
Retraction: Hsa_circ_0003645 Shows an Oncogenic Role by Sponging microRNA-1299 in Hepatocellular Carcinoma Cells
Cell Counting Kit-8 purchased from AbMole -
Saudi J Gastroenterol. 2020 May-Jun;26(3):144-152.
Inhibition of ALAS1 Activity Exerts Anti-Tumour Effects on Colorectal Cancer in vitro
Cell Counting Kit-8 purchased from AbMole -
Anat Rec (Hoboken). 2020 Jan 21.
Resibufogenin inhibited colorectal cancer cell growth and tumorigenesis through triggering ferroptosis and ROS production mediated by GPX4 inactivation
Cell Counting Kit-8 purchased from AbMole -
Anat Rec (Hoboken). 2020 Jan 21.
Resibufogenin inhibited colorectal cancer cell growth and tumorigenesis through triggering ferroptosis and ROS production mediated by GPX4 inactivation.
Cell Counting Kit-8 purchased from AbMole -
Open Life Sciences. 2020 Jun 30;15(1):409-417.
Buformin suppresses osteosarcoma via targeting AMPK signaling pathway
Cell Counting Kit-8 purchased from AbMole -
2020 Jun.
The Role of Transcription Factor Ap1 in The Activation of Nrf2/ARE Pathway Through TET1 in Diabetic Nephropathy
Cell Counting Kit-8 purchased from AbMole -
2020 Aug.
Blockage of AMPK-ULK1 pathway mediated autophagy promotes cell apoptosis to increase doxorubicin sensitivity in breast cancer (BC) cells: an in vitro study
Cell Counting Kit-8 purchased from AbMole -
2020 Dec.
A Novel Circular RNA hsa_circRNA_103809/miR-377-3p/GOT1 Pathway Regulates Cisplatin-Resistance in Non-Small Cell Lung Cancer (NSCLC)
Cell Counting Kit-8 purchased from AbMole -
2020 Aug.
Blockage of AMPK-ULK1 pathway mediated autophagy promotes cell apoptosis to increase doxorubicin sensitivity in breast cancer (BC) cells: an in vitro study
Cell Counting Kit-8 purchased from AbMole -
International Journal of Oncology. 2019 Mar;929-941.
lncRNA H19 promotes viability and epithelial-mesenchymal transition of lung adenocarcinoma cells by targeting miR-29b-3p and modifying STAT3.
Cell Counting Kit-8 purchased from AbMole -
Biochem Biophys Res Commun. 2019 Apr 30;512(2):218-223.
Versatile Pt NCs-based chemotherapeutic agents significantly induce the apoptosis of cisplatin-resistant non-small cell lung cancer.
Cell Counting Kit-8 purchased from AbMole -
Med Sci Monit. 2019 Aug 11;25:5977-5985.
Expression of circZNF609 is Down-Regulated in Colorectal Cancer Tissue and Promotes Apoptosis in Colorectal Cancer Cells by Upregulating p53.
Cell Counting Kit-8 purchased from AbMole -
Oncol Lett. 2019 Nov;18(5):4613-4620.
MicroRNA-152 suppresses cisplatin resistance in A549 cells.
Cell Counting Kit-8 purchased from AbMole -
Yonsei Med J. 2019 Sep;60(9):832-841.
miR-1301/TRIAP1 Axis Participates in Epirubicin-Mediated Anti-Proliferation and Pro-Apoptosis in Osteosarcoma.
Cell Counting Kit-8 purchased from AbMole -
J Clin Neurosci. 2019 Jun;64:234-241.
Potential contribution of microRNA-125b targeting p38MAPK to relieving intermittent hypoxia-induced dementia of rat models.
Cell Counting Kit-8 purchased from AbMole -
Sci Rep. 2018 Mar 1;8(1):3891.
Bufalin suppresses hepatocarcinogenesis by targeting β-catenin/TCF signaling via cell cycle-related kinase
Cell Counting Kit-8 purchased from AbMole -
Int J Pharm. 2018 Dec 13;556:338-348.
Self-implanted tiny needles as alternative to traditional parenteral administrations for controlled transdermal drug delivery.
Cell Counting Kit-8 purchased from AbMole -
Cancer Biol Ther. 2018 Feb 5.
Buformin suppresses proliferation and invasion via AMPK/S6 pathway in cervical cancer and synergizes with paclitaxel
Cell Counting Kit-8 purchased from AbMole -
Future Oncology. 2018 Jan 10.
The overexpression of PXN promotes tumor progression and leads to radioresistance in cervical cancer
Cell Counting Kit-8 purchased from AbMole -
Med Sci Monit. 2018 Oct 28;24:7710-7718.
Knockdown of MON1B Exerts Anti-Tumor Effects in Colon Cancer In Vitro.
Cell Counting Kit-8 purchased from AbMole