Chicken CD8b Antibody : FITC
Cat# OASB02422
Size : 0.5mg
Brand : Aviva Systems Biology
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Phone : +1 850 650 7790
Chicken CD8b Antibody : FITC (OASB02422)
| Datasheets/Manuals | Printable datasheet for Chicken CD8b Antibody : FITC (OASB02422) |
|---|
| Tested Species Reactivity | Chicken |
|---|---|
| Predicted Species Reactivity | Chicken |
| Product Format | Liquid. Phosphate buffered saline containing 0.1% sodium azide |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugation | FITC |
| Application | FC, IHC-F |
| Additional Information | Description: In the chicken, the CD8 molecule is present in two forms - (i) a homodimer of two alpha chains and (ii) a heterodimer of an alpha chain and a beta chain. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8 alpha- and CD8 beta-chains, a relatively large proportion of the CD8+ TCR gamma/delta cells in the spleens of embryos and young chicks express only the alpha-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved but there is a population of TCR gamma/delta CD8 alpha/beta cells in the chicken that is not found in rodents. Chicken CD8 is expressed on approximately 80% of thymocytes, 45% of blood mononuclear cells, and 50% of spleen cells but less than 1% of cells in the bursa and bone marrow. The monoclonal antibody EP42 recognizes the CD8 beta chain. |
| Reconstitution and Storage | Store at 2-8C |
| Immunogen | Chicken splenocytes |
| Concentration | 0.5 mg/mL |
| Specificity | CD8b |
| Gene Symbol | CD8BP |
|---|---|
| Alias Symbols | CD8B, CD8B1 |
| NCBI Gene Id | 396175 |
| Protein Name | T-cell surface glycoprotein CD8 beta chain |
| Uniprot ID | F6RFK3 |
| Protein Accession # | NP_990578.2 |
| Nucleotide Accession # | NM_205247.2 |
