Colchicine-d6 [1217651-73-4]
Cat# HY-16569S-1mg
Size : 1mg
Brand : MedChemExpress
Colchicine-d6 is the deuterium labeled Colchicine. Colchicine is a tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM[1][2][3]. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs)[4].
For research use only. We do not sell to patients.
Colchicine-d6 Chemical Structure
CAS No. : 1217651-73-4
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Other Forms of Colchicine-d6:
- Colchicine In-stock
View All NOD-like Receptor (NLR) Isoform Specific Products:
Description |
Colchicine-d6 is the deuterium labeled Colchicine. Colchicine is a tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM[1][2][3]. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs)[4]. |
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In Vitro |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
Molecular Weight |
405.47 |
Formula |
C22H19D6NO6 |
CAS No. |
1217651-73-4 |
Unlabeled CAS |
64-86-8 |
SMILES |
COC1=C(C(OC)=CC2=C1C(C([C@H](CC2)NC(C([2H])([2H])[2H])=O)=CC3=O)=CC=C3OC([2H])([2H])[2H])OC |
Shipping | Room temperature in continental US; may vary elsewhere. |
Storage |
Please store the product under the recommended conditions in the Certificate of Analysis. |
Purity & Documentation | |
References |
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Colchicine-d6 Related Classifications
- Cancer
- Cancer Targeted Therapy Cancer Immunotherapy Cancer Metabolism and Metastasis
- Others Cell Cycle/DNA Damage Cytoskeleton Immunology/Inflammation Autophagy Apoptosis
- Isotope-Labeled Compounds Microtubule/Tubulin NOD-like Receptor (NLR) Autophagy Apoptosis
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Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
Keywords:
Colchicine-d61217651-73-4Isotope-Labeled CompoundsMicrotubule/TubulinNOD-like Receptor (NLR)AutophagyApoptosisInhibitorinhibitorinhibit