DABCYL Acid

DABCYL Acid
Catalog number: B2011416
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: 269.3 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: DABCYL acid [4-((4-(dimethylamino)phenyl)azo)benzoic acid]
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Tyagi S, Kramer FR. Molecular beacons: probes that fluoresce upon hybridization Nat Biotechnol. 1996 Mar;14(3):303-8.
2: Mandal S, Mann G, Satish G, Brik A. Enhanced Live-Cell Delivery of Synthetic Proteins Assisted by Cell-Penetrating Peptides Fused to DABCYL Angew Chem Int Ed Engl. 2021 Mar 22;60(13):7333-7343.
3: Zhang X, Kotikam V, Rozners E, Callahan BP. Enzymatic Beacons for Specific Sensing of Dilute Nucleic Acid and Potential Utility for SARS-CoV-2 Detection bioRxiv. 2021 Aug 31:2021.08.30.458287.
4: Szabó I, Illien F, Dókus LE, Yousef M, Baranyai Z, Bősze S, Ise S, Kawano K, Sagan S, Futaki S, Hudecz F, Bánóczi Z. Influence of the Dabcyl group on the cellular uptake of cationic peptides: short oligoarginines as efficient cell-penetrating peptides Amino Acids. 2021 Jul;53(7):1033-1049.
5: Kempf O, Kempf K, Schobert R, Bombarda E. Hydrodabcyl: A Superior Hydrophilic Alternative to the Dark Fluorescence Quencher Dabcyl Anal Chem. 2017 Nov 21;89(22):11893-11897.
6: Harmon NM, Huang X, Hsiao CC, Wiemer AJ, Wiemer DF. Incorporation of a FRET pair within a phosphonate diester Bioorg Chem. 2021 Sep;114:105048.
7: Grytsyk N, Cianfarani D, Crégut O, Richert L, Boudier C, Humbert N, Didier P, Mély Y, Léonard J. Kinetics of protein-assisted nucleic acid interconversion monitored by transient time resolved fluorescence in microfluidic droplets Nucleic Acids Res. 2021 Nov 8;49(19):e111.
8: Alvarado-González M, Gallo M, Lopez-Albarran P, Flores-Holguín N, Glossman-Mitnik D. DFT study of the interaction between the conjugated fluorescein and dabcyl system, using fluorescene quenching method J Mol Model. 2012 Sep;18(9):4113-20.
9: Zhang X, Kotikam V, Rozners E, Callahan BP. Enzymatic Beacons for Specific Sensing of Dilute Nucleic Acid Chembiochem. 2022 Feb 16;23(4):e202100594.
10: Hofstetter O, Hofstetter H, Miron T, Wilchek M. The conversion of azo-quenchers to fluorophores Anal Biochem. 2019 Nov 15;585:113400.

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