FAM111A (NM_198847) Human 3' UTR Clone
Cat# SC215229
Size : 10µg
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| Product Data | |
| Vector | pMirTarget |
|---|---|
| Species | Human |
| Transfection Reporter | RFP |
| Assay Reporter | Luciferase |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Target Symbol | FAM111A |
| Synonyms | GCLEB; KCS2 |
| ACCN | NM_198847 |
| Insert Size | 1565 bp |
| Sequence Data | Insert Sequence >SC215229 3’UTR clone of NM_198847 The sequence shown below is from the reference sequence of NM_198847. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTAGAAATGATGAGTGATGAGGACTTGTGAGAATTCAGTCTACTGGATTTAAGGGAATGGCTTATGGAG TTGTTATTTCATAGGCATTGAAAATGGTTTTCTAAACTCCAAAATGGTCATCTTATCAATAATAATAAT ATTGACCATTTCCTATCTGCCAGGCATTTTTCTAAGCACATGAAGAAATTAGTCCTAACAACACTATGA GATGGACTATAACTTGCCCAAATTTTTTTTTTTTTTTTGAGACTGAGTCTCACTCTGTCGCCTGGGCTG GAGTACAGTGGTGCGATCTCAGCTCACTGCAACTTCCACCTCCCAGGTTCAAGCGATTCTTATGCCTCA GTCTCCTGAGCAGCTGGGATTACAGGCAAACGCCACCACACCCAGCTAAATTTTTTTTTTTTTTTTTGT ATTTTTAGTAGAGACAGGGTTTCACCATGTTGGTCAGGCGGGTCTCGAACTCCTGACCTCGTGATCCAC CTGCCTCGGCCTTCCAAAGTGCTGGGATTACAAGTTTGAGCCACTGCACCTGGCTAACTTGCCCTATTT TAAAGTCAAGCAATGGGAAGAATAACAAGATTATATAGTAATCAGTTTCATGACACTAAAAGTCATATA GTCATAGGGTTTTTTCATCTTTCATATCTTTGCCTAAATTCATTTGCTACAGTGCAGGAACCAAAACTT GTTCATCTCATGATTCCCTACATCTGACATAAGGAAAGTAAGTGCTCAGAAAAATGTGCAGGTCAATAA GTTGCAAAAGTTGGGGCTGCAATTAATGCTAACATAAGAGCTAAATGCTTGATTAGAAATGATCTCAAA ACCTTTTAGAATTTCCAAAATCTTCATATTACTGAAACTGTCGGAATATATGGGTCTTGAAATTCAGAA GATGATAGTCACTCTTCCCATATTTATAGGCTATTAAGGCAAGGGATATCTTAAACATCATATTACTTT ATTTAGATTTCTACTACTCCAATTATTAATGTTATGTATTTCTCATTGTTTTACTTCTTCATGGTATTA TGAAGACTATATAGATGATTCAACCAAGCCTGCAAATCTCCCTCTTGTGGAATTCCACTGGACCCAATC TGTTTTCCATTTCCATTGCAATACTACTAAAGCCATACAATATCAAGCACCCTCCCTCTAGGTCCAGGG ACTATCACAGAAGAAGCAGGCATGTAAGATTTTAAGGACTGGTTTCGAGGGGTCGAGTGTAGGAAAACA GCCTGTTGCATTGTAAGAGTGATGTCATCTTGAAGAGCAGCTGGCATGATGACTGCTGTTTGACTCCTG CATACCAAGATATTCTGCAGCAATGTCTTTAAACAGTGCCGGTAGTACAGATAACCCCTCATAAAGATG CTTATCTAACCTCCCCAGTGTTCAGGTGTTTCACAAGAAAGTCTGAGATATGACTAGCTACACGTTTTG CCAAAAATGCTTGTTATATAAAGGGTACTTTTGGGAGGGTGAGTGCCGCCATTTAGTGGCTGCTAGAAA CATTGCTTCTGTTTGTAAGTTCCTATTAAATGTTTCTTTCTGAGAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
| Restriction Sites | SgfI-MluI |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
| Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_198847.3 |
| Locus ID | 63901 |
| Summary | The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia), both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] |
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