Human Glutathione Peroxidase 7 (GPX7) activation kit by CRISPRa

CAT#: GA101940

GPX7 CRISPRa kit - CRISPR gene activation of human glutathione peroxidase 7



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol GPX7
Locus ID 2882
Kit Components

GA101940G1, Glutathione Peroxidase 7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101940G2, Glutathione Peroxidase 7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101940G3, Glutathione Peroxidase 7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_015696
UniProt ID Q96SL4
Synonyms CL683; GPx-7; GPX6; GSHPx-7; NPGPx
Summary It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks.[UniProtKB/Swiss-Prot Function]

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