Human Glutathione Reductase (GSR) activation kit by CRISPRa

Cat# GA101986

Size : 1kit

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Human Glutathione Reductase (GSR) activation kit by CRISPRa

SKU
GA101986
GSR CRISPRa kit - CRISPR gene activation of human glutathione-disulfide reductase
2 Weeks*
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GSR
Locus ID 2936
Components

GA101986G1, Glutathione Reductase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101986G2, Glutathione Reductase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101986G3, Glutathione Reductase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000637, NM_001195102, NM_001195103, NM_001195104
UniProt ID P00390
Synonyms HEL-75
Summary This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010]
SKU Description Size
KN409652 GSR - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit

Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.