Human Glycerol 3 Phosphate Dehydrogenase (GPD1) activation kit by CRISPRa
Cat# GA101884
Size : 1kit
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Human Glycerol 3 Phosphate Dehydrogenase (GPD1) activation kit by CRISPRa
SKU
GA101884
GPD1 CRISPRa kit - CRISPR gene activation of human glycerol-3-phosphate dehydrogenase 1
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | GPD1 |
| Locus ID | 2819 |
| Components | GA101884G1, Glycerol 3 Phosphate Dehydrogenase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101884G2, Glycerol 3 Phosphate Dehydrogenase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101884G3, Glycerol 3 Phosphate Dehydrogenase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001257199, NM_005276 |
| UniProt ID | P21695 |
| Synonyms | GPD-C; GPDH-C; HTGTI |
| Summary | This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN406538 | GPD1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.