Human Metabotropic Glutamate Receptor 5 (GRM5) activation kit by CRISPRa
Cat# GA101970
Size : 1kit
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Human Metabotropic Glutamate Receptor 5 (GRM5) activation kit by CRISPRa
SKU
GA101970
GRM5 CRISPRa kit - CRISPR gene activation of human glutamate metabotropic receptor 5
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | GRM5 |
| Locus ID | 2915 |
| Components | GA101970G1, Metabotropic Glutamate Receptor 5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101970G2, Metabotropic Glutamate Receptor 5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101970G3, Metabotropic Glutamate Receptor 5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_000842, NM_001143831 |
| UniProt ID | P41594 |
| Synonyms | GPRC1E; mGlu5; MGLUR5; PPP1R86 |
| Summary | This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN416892 | GRM5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.